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Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Johnson CE, Huang YY, Parrish AB, Smith MI, Vaughn AE, Zhang Q, Wright KM, Van Dyke T, Wechsler-Reya RJ, Kornbluth S, Deshmukh M. Johnson CE, et al. Among authors: kornbluth s. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20820-5. doi: 10.1073/pnas.0709101105. Epub 2007 Dec 18. Proc Natl Acad Sci U S A. 2007. PMID: 18093951 Free PMC article.
Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.
Kurokawa M, Ito T, Yang CS, Zhao C, Macintyre AN, Rizzieri DA, Rathmell JC, Deininger MW, Reya T, Kornbluth S. Kurokawa M, et al. Among authors: kornbluth s. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2300-5. doi: 10.1073/pnas.1206551110. Epub 2013 Jan 16. Proc Natl Acad Sci U S A. 2013. PMID: 23324740 Free PMC article.
Ubiquitylation of p53 by the APC/C inhibitor Trim39.
Zhang L, Huang NJ, Chen C, Tang W, Kornbluth S. Zhang L, et al. Among authors: kornbluth s. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20931-6. doi: 10.1073/pnas.1212047110. Epub 2012 Dec 4. Proc Natl Acad Sci U S A. 2012. PMID: 23213260 Free PMC article.
Caspase cleavage is not for everyone.
Johnson CE, Kornbluth S. Johnson CE, et al. Among authors: kornbluth s. Cell. 2008 Sep 5;134(5):720-1. doi: 10.1016/j.cell.2008.08.019. Cell. 2008. PMID: 18775303 Free article.
124 results