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Pharmacodynamics of TD-1792, a novel glycopeptide-cephalosporin heterodimer antibiotic used against Gram-positive bacteria, in a neutropenic murine thigh model.
Hegde SS, Okusanya OO, Skinner R, Shaw JP, Obedencio G, Ambrose PG, Blais J, Bhavnani SM. Hegde SS, et al. Among authors: shaw jp. Antimicrob Agents Chemother. 2012 Mar;56(3):1578-83. doi: 10.1128/AAC.05382-11. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155835 Free PMC article.
A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma.
Long DD, Frieman B, Hegde SS, Hill CM, Jiang L, Kintz S, Marquess DG, Purkey H, Shaw JP, Steinfeld T, Wilson MS, Wrench K. Long DD, et al. Among authors: shaw jp. Bioorg Med Chem Lett. 2013 Feb 15;23(4):939-43. doi: 10.1016/j.bmcl.2012.12.058. Epub 2012 Dec 22. Bioorg Med Chem Lett. 2013. PMID: 23317571
Intrapulmonary distribution of intravenous telavancin in healthy subjects and effect of pulmonary surfactant on in vitro activities of telavancin and other antibiotics.
Gotfried MH, Shaw JP, Benton BM, Krause KM, Goldberg MR, Kitt MM, Barriere SL. Gotfried MH, et al. Among authors: shaw jp. Antimicrob Agents Chemother. 2008 Jan;52(1):92-7. doi: 10.1128/AAC.00875-07. Epub 2007 Oct 8. Antimicrob Agents Chemother. 2008. PMID: 17923490 Free PMC article. Clinical Trial.
Hydrophobic vancomycin derivatives with improved ADME properties: discovery of telavancin (TD-6424).
Leadbetter MR, Adams SM, Bazzini B, Fatheree PR, Karr DE, Krause KM, Lam BM, Linsell MS, Nodwell MB, Pace JL, Quast K, Shaw JP, Soriano E, Trapp SG, Villena JD, Wu TX, Christensen BG, Judice JK. Leadbetter MR, et al. Among authors: shaw jp. J Antibiot (Tokyo). 2004 May;57(5):326-36. doi: 10.7164/antibiotics.57.326. J Antibiot (Tokyo). 2004. PMID: 15303493 Free article.
Vancomycin disulfide derivatives as antibacterial agents.
Mu Y, Nodwell M, Pace JL, Shaw JP, Judice JK. Mu Y, et al. Among authors: shaw jp. Bioorg Med Chem Lett. 2004 Feb 9;14(3):735-8. doi: 10.1016/j.bmcl.2003.11.040. Bioorg Med Chem Lett. 2004. PMID: 14741279
144 results