Jonckheere W - Search Results

1

Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease.

Pauwels K, Williams TL, Morris KL, Jonckheere W, Vandersteen A, Kelly G, Schymkowitz J, Rousseau F, Pastore A, Serpell LC, Broersen K. Pauwels K, et al. Among authors: jonckheere w. J Biol Chem. 2012 Feb 17;287(8):5650-60. doi: 10.1074/jbc.M111.264473. Epub 2011 Dec 8. J Biol Chem. 2012. PMID: 22157754 Free PMC article.

2

Molecular plasticity regulates oligomerization and cytotoxicity of the multipeptide-length amyloid-β peptide pool.

Vandersteen A, Masman MF, De Baets G, Jonckheere W, van der Werf K, Marrink SJ, Rozenski J, Benilova I, De Strooper B, Subramaniam V, Schymkowitz J, Rousseau F, Broersen K. Vandersteen A, et al. Among authors: jonckheere w. J Biol Chem. 2012 Oct 26;287(44):36732-43. doi: 10.1074/jbc.M112.394635. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992745 Free PMC article.

3

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.

Kuperstein I, Broersen K, Benilova I, Rozenski J, Jonckheere W, Debulpaep M, Vandersteen A, Segers-Nolten I, Van Der Werf K, Subramaniam V, Braeken D, Callewaert G, Bartic C, D'Hooge R, Martins IC, Rousseau F, Schymkowitz J, De Strooper B. Kuperstein I, et al. Among authors: jonckheere w. EMBO J. 2010 Oct 6;29(19):3408-20. doi: 10.1038/emboj.2010.211. Epub 2010 Sep 3. EMBO J. 2010. PMID: 20818335 Free PMC article.

4

A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease.

Broersen K, Jonckheere W, Rozenski J, Vandersteen A, Pauwels K, Pastore A, Rousseau F, Schymkowitz J. Broersen K, et al. Among authors: jonckheere w. Protein Eng Des Sel. 2011 Sep;24(9):743-50. doi: 10.1093/protein/gzr020. Epub 2011 May 11. Protein Eng Des Sel. 2011. PMID: 21565831 Free article.

5

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice.

Martins IC, Kuperstein I, Wilkinson H, Maes E, Vanbrabant M, Jonckheere W, Van Gelder P, Hartmann D, D'Hooge R, De Strooper B, Schymkowitz J, Rousseau F. Martins IC, et al. Among authors: jonckheere w. EMBO J. 2008 Jan 9;27(1):224-33. doi: 10.1038/sj.emboj.7601953. Epub 2007 Dec 6. EMBO J. 2008. PMID: 18059472 Free PMC article.

6

Selectivity of aggregation-determining interactions.

Ganesan A, Debulpaep M, Wilkinson H, Van Durme J, De Baets G, Jonckheere W, Ramakers M, Ivarsson Y, Zimmermann P, Van Eldere J, Schymkowitz J, Rousseau F. Ganesan A, et al. Among authors: jonckheere w. J Mol Biol. 2015 Jan 30;427(2):236-47. doi: 10.1016/j.jmb.2014.09.027. Epub 2014 Nov 7. J Mol Biol. 2015. PMID: 25451783

7

Aggregation gatekeepers modulate protein homeostasis of aggregating sequences and affect bacterial fitness.

Beerten J, Jonckheere W, Rudyak S, Xu J, Wilkinson H, De Smet F, Schymkowitz J, Rousseau F. Beerten J, et al. Among authors: jonckheere w. Protein Eng Des Sel. 2012 Jul;25(7):357-66. doi: 10.1093/protein/gzs031. Epub 2012 Jun 15. Protein Eng Des Sel. 2012. PMID: 22706763 Free article.

8

Crystallization and preliminary X-ray crystallographic analysis of the curli transporter CsgG.

Goyal P, Van Gerven N, Jonckheere W, Remaut H. Goyal P, et al. Among authors: jonckheere w. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1349-53. doi: 10.1107/S1744309113028054. Epub 2013 Nov 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 24316827 Free PMC article.

9

Nucleation and growth of a bacterial functional amyloid at single-fiber resolution.

Sleutel M, Van den Broeck I, Van Gerven N, Feuillie C, Jonckheere W, Valotteau C, Dufrêne YF, Remaut H. Sleutel M, et al. Among authors: jonckheere w. Nat Chem Biol. 2017 Aug;13(8):902-908. doi: 10.1038/nchembio.2413. Epub 2017 Jun 19. Nat Chem Biol. 2017. PMID: 28628096 Free PMC article.

10

Secretion and functional display of fusion proteins through the curli biogenesis pathway.

Van Gerven N, Goyal P, Vandenbussche G, De Kerpel M, Jonckheere W, De Greve H, Remaut H. Van Gerven N, et al. Among authors: jonckheere w. Mol Microbiol. 2014 Mar;91(5):1022-35. doi: 10.1111/mmi.12515. Epub 2014 Feb 12. Mol Microbiol. 2014. PMID: 24417346 Free article.

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