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Page 1
Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine.
Lavelle D, Vaitkus K, Ling Y, Ruiz MA, Mahfouz R, Ng KP, Negrotto S, Smith N, Terse P, Engelke KJ, Covey J, Chan KK, Desimone J, Saunthararajah Y. Lavelle D, et al. Among authors: desimone j. Blood. 2012 Feb 2;119(5):1240-7. doi: 10.1182/blood-2011-08-371690. Epub 2011 Dec 7. Blood. 2012. PMID: 22160381 Free PMC article.
Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.
Molokie R, Lavelle D, Gowhari M, Pacini M, Krauz L, Hassan J, Ibanez V, Ruiz MA, Ng KP, Woost P, Radivoyevitch T, Pacelli D, Fada S, Rump M, Hsieh M, Tisdale JF, Jacobberger J, Phelps M, Engel JD, Saraf S, Hsu LL, Gordeuk V, DeSimone J, Saunthararajah Y. Molokie R, et al. Among authors: desimone j. PLoS Med. 2017 Sep 7;14(9):e1002382. doi: 10.1371/journal.pmed.1002382. eCollection 2017 Sep. PLoS Med. 2017. PMID: 28880867 Free PMC article. Clinical Trial.
Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease.
Saunthararajah Y, Hillery CA, Lavelle D, Molokie R, Dorn L, Bressler L, Gavazova S, Chen YH, Hoffman R, DeSimone J. Saunthararajah Y, et al. Among authors: desimone j. Blood. 2003 Dec 1;102(12):3865-70. doi: 10.1182/blood-2003-05-1738. Epub 2003 Aug 7. Blood. 2003. PMID: 12907443 Free article. Clinical Trial.
DNA hypo-methylating agents and sickle cell disease.
Saunthararajah Y, Lavelle D, DeSimone J. Saunthararajah Y, et al. Among authors: desimone j. Br J Haematol. 2004 Sep;126(5):629-36. doi: 10.1111/j.1365-2141.2004.05064.x. Br J Haematol. 2004. PMID: 15327513 Free article. Review.
471 results