Levova K - Search Results

1

Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver.

Stiborova M, Mares J, Levova K, Pavlickova J, Barta F, Hodek P, Frei E, Schmeiser HH. Stiborova M, et al. Among authors: levova k. Neuro Endocrinol Lett. 2011;32 Suppl 1:121-30. Neuro Endocrinol Lett. 2011. PMID: 22167220

2

Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.

Levová K, Moserová M, Kotrbová V, Sulc M, Henderson CJ, Wolf CR, Phillips DH, Frei E, Schmeiser HH, Mares J, Arlt VM, Stiborová M. Levová K, et al. Toxicol Sci. 2011 May;121(1):43-56. doi: 10.1093/toxsci/kfr050. Epub 2011 Feb 28. Toxicol Sci. 2011. PMID: 21362632 Free article.

3

Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.

Arlt VM, Levová K, Bárta F, Shi Z, Evans JD, Frei E, Schmeiser HH, Nebert DW, Phillips DH, Stiborová M. Arlt VM, et al. Among authors: levova k. Chem Res Toxicol. 2011 Oct 17;24(10):1710-9. doi: 10.1021/tx200259y. Epub 2011 Sep 29. Chem Res Toxicol. 2011. PMID: 21932800

4

Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.

Stiborová M, Levová K, Bárta F, Shi Z, Frei E, Schmeiser HH, Nebert DW, Phillips DH, Arlt VM. Stiborová M, et al. Among authors: levova k. Toxicol Sci. 2012 Feb;125(2):345-58. doi: 10.1093/toxsci/kfr306. Epub 2011 Nov 15. Toxicol Sci. 2012. PMID: 22086975 Free PMC article.

5

NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I.

Levova K, Moserova M, Nebert DW, Phillips DH, Frei E, Schmeiser HH, Arlt VM, Stiborova M. Levova K, et al. Toxicol Appl Pharmacol. 2012 Dec 15;265(3):360-7. doi: 10.1016/j.taap.2012.09.004. Epub 2012 Sep 13. Toxicol Appl Pharmacol. 2012. PMID: 22982977

6

The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats.

Stiborová M, Levová K, Bárta F, Šulc M, Frei E, Arlt VM, Schmeiser HH. Stiborová M, et al. Among authors: levova k. Mutagenesis. 2014 May;29(3):189-200. doi: 10.1093/mutage/geu004. Epub 2014 Mar 5. Mutagenesis. 2014. PMID: 24598128

7

The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats--a comparative study.

Bárta F, Levová K, Frei E, Schmeiser HH, Arlt VM, Stiborová M. Bárta F, et al. Among authors: levova k. Mutat Res Genet Toxicol Environ Mutagen. 2014 Jul 1;768:1-7. doi: 10.1016/j.mrgentox.2014.01.012. Epub 2014 Apr 24. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 24769487 Free article.

8

The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats.

Stiborová M, Bárta F, Levová K, Hodek P, Frei E, Arlt VM, Schmeiser HH. Stiborová M, et al. Among authors: levova k. Arch Toxicol. 2015 Nov;89(11):2141-58. doi: 10.1007/s00204-014-1360-1. Epub 2014 Sep 11. Arch Toxicol. 2015. PMID: 25209566

9

Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo.

Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt VM, Schmeiser HH. Stiborova M, et al. Among authors: levova k. Neuro Endocrinol Lett. 2014;35 Suppl 2:123-32. Neuro Endocrinol Lett. 2014. PMID: 25638376

10

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.

Stiborová M, Bárta F, Levová K, Hodek P, Schmeiser HH, Arlt VM, Martínek V. Stiborová M, et al. Among authors: levova k. Int J Mol Sci. 2015 Nov 18;16(11):27561-75. doi: 10.3390/ijms161126047. Int J Mol Sci. 2015. PMID: 26593908 Free PMC article.

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