Stiborova M - Search Results

1

Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver.

Stiborova M, Mares J, Levova K, Pavlickova J, Barta F, Hodek P, Frei E, Schmeiser HH. Stiborova M, et al. Neuro Endocrinol Lett. 2011;32 Suppl 1:121-30. Neuro Endocrinol Lett. 2011. PMID: 22167220

2

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Stiborová M, Martínek V, Rýdlová H, Hodek P, Frei E. Stiborová M, et al. Cancer Res. 2002 Oct 15;62(20):5678-84. Cancer Res. 2002. PMID: 12384524

3

Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

Stiborová M, Frei E, Sopko B, Sopková K, Marková V, Lanková M, Kumstýrová T, Wiessler M, Schmeiser HH. Stiborová M, et al. Carcinogenesis. 2003 Oct;24(10):1695-703. doi: 10.1093/carcin/bgg119. Epub 2003 Jul 17. Carcinogenesis. 2003. PMID: 12869422

4

Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.

Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M. Miksanová M, et al. Among authors: stiborova m. Chem Res Toxicol. 2004 May;17(5):663-71. doi: 10.1021/tx0499721. Chem Res Toxicol. 2004. PMID: 15144223

5

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410

6

Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

Stiborová M, Martínek V, Rýdlová H, Koblas T, Hodek P. Stiborová M, et al. Cancer Lett. 2005 Apr 8;220(2):145-54. doi: 10.1016/j.canlet.2004.07.036. Cancer Lett. 2005. PMID: 15766589

7

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.

Stiborová M, Sopko B, Hodek P, Frei E, Schmeiser HH, Hudecek J. Stiborová M, et al. Cancer Lett. 2005 Nov 18;229(2):193-204. doi: 10.1016/j.canlet.2005.06.038. Epub 2005 Aug 24. Cancer Lett. 2005. PMID: 16125300

8

Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone.

Stiborová M, Arlt VM, Henderson CJ, Wolf CR, Frei E, Schmeiser HH, Phillips DH. Stiborová M, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec;149(2):191-7. doi: 10.5507/bp.2005.025. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005. PMID: 16601755 Review.

9

The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase.

Stiborová M, Dracínská H, Hájková J, Kaderábková P, Frei E, Schmeiser HH, Soucek P, Phillips DH, Arlt VM. Stiborová M, et al. Drug Metab Dispos. 2006 Aug;34(8):1398-405. doi: 10.1124/dmd.106.009373. Epub 2006 May 19. Drug Metab Dispos. 2006. PMID: 16714372

10

Molecular mechanisms of antineoplastic action of an anticancer drug ellipticine.

Stiborova M, Rupertova M, Schmeiser HH, Frei E. Stiborova M, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2006 Jul;150(1):13-23. doi: 10.5507/bp.2006.002. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2006. PMID: 16936898 Review.

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