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21 results

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Page 1
Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates.
Woodman SE, Trent JC, Stemke-Hale K, Lazar AJ, Pricl S, Pavan GM, Fermeglia M, Gopal YN, Yang D, Podoloff DA, Ivan D, Kim KB, Papadopoulos N, Hwu P, Mills GB, Davies MA. Woodman SE, et al. Among authors: gopal yn. Mol Cancer Ther. 2009 Aug;8(8):2079-85. doi: 10.1158/1535-7163.MCT-09-0459. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671763 Free PMC article.
Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma.
Davies MA, Stemke-Hale K, Lin E, Tellez C, Deng W, Gopal YN, Woodman SE, Calderone TC, Ju Z, Lazar AJ, Prieto VG, Aldape K, Mills GB, Gershenwald JE. Davies MA, et al. Among authors: gopal yn. Clin Cancer Res. 2009 Dec 15;15(24):7538-7546. doi: 10.1158/1078-0432.CCR-09-1985. Clin Cancer Res. 2009. PMID: 19996208 Free PMC article.
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Mao M, Tian F, Mariadason JM, Tsao CC, Lemos R Jr, Dayyani F, Gopal YN, Jiang ZQ, Wistuba II, Tang XM, Bornman WG, Bollag G, Mills GB, Powis G, Desai J, Gallick GE, Davies MA, Kopetz S. Mao M, et al. Among authors: gopal yn. Clin Cancer Res. 2013 Feb 1;19(3):657-67. doi: 10.1158/1078-0432.CCR-11-1446. Epub 2012 Dec 18. Clin Cancer Res. 2013. PMID: 23251002 Free PMC article.
Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target.
Chen G, Chakravarti N, Aardalen K, Lazar AJ, Tetzlaff MT, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Chen G, et al. Among authors: gopal yn. Clin Cancer Res. 2014 Nov 1;20(21):5537-46. doi: 10.1158/1078-0432.CCR-13-3003. Epub 2014 May 6. Clin Cancer Res. 2014. PMID: 24803579 Free PMC article.
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma.
Gopal YN, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, Scolyer RA, Pupo G, Komurov K, Sehgal V, Zhang J, Patel L, Pereira CG, Broom BM, Mills GB, Ram P, Smith PD, Wargo JA, Long GV, Davies MA. Gopal YN, et al. Cancer Res. 2014 Dec 1;74(23):7037-47. doi: 10.1158/0008-5472.CAN-14-1392. Epub 2014 Oct 8. Cancer Res. 2014. PMID: 25297634 Free PMC article.
Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays.
Li J, Zhao W, Akbani R, Liu W, Ju Z, Ling S, Vellano CP, Roebuck P, Yu Q, Eterovic AK, Byers LA, Davies MA, Deng W, Gopal YN, Chen G, von Euw EM, Slamon D, Conklin D, Heymach JV, Gazdar AF, Minna JD, Myers JN, Lu Y, Mills GB, Liang H. Li J, et al. Among authors: gopal yn. Cancer Cell. 2017 Feb 13;31(2):225-239. doi: 10.1016/j.ccell.2017.01.005. Cancer Cell. 2017. PMID: 28196595 Free PMC article.
ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma.
Ndoye A, Budina-Kolomets A, Kugel CH 3rd, Webster MR, Kaur A, Behera R, Rebecca VW, Li L, Brafford PA, Liu Q, Gopal YNV, Davies MA, Mills GB, Xu X, Wu H, Herlyn M, Nicastri MC, Winkler JD, Soengas MS, Amaravadi RK, Murphy ME, Weeraratna AT. Ndoye A, et al. Among authors: gopal ynv. Cancer Res. 2017 Nov 1;77(21):5873-5885. doi: 10.1158/0008-5472.CAN-17-0907. Epub 2017 Sep 8. Cancer Res. 2017. PMID: 28887323 Free PMC article.
Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.
Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Cascone T, et al. Among authors: gopal ynv. Cell Metab. 2018 May 1;27(5):977-987.e4. doi: 10.1016/j.cmet.2018.02.024. Epub 2018 Apr 5. Cell Metab. 2018. PMID: 29628419 Free PMC article.
21 results