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4,478 results

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Page 1
Discovery of novel and potent CRTH2 antagonists.
Ito S, Terasaka T, Zenkoh T, Matsuda H, Hayashida H, Nagata H, Imamura Y, Kobayashi M, Takeuchi M, Ohta M. Ito S, et al. Among authors: takeuchi m. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1194-7. doi: 10.1016/j.bmcl.2011.11.079. Epub 2011 Nov 28. Bioorg Med Chem Lett. 2012. PMID: 22178554
Synthesis and structure-activity relationships of N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide derivatives as novel CCR3 antagonists.
Sato I, Morihira K, Inami H, Kubota H, Morokata T, Suzuki K, Hamada N, Iura Y, Nitta A, Imaoka T, Takahashi T, Takeuchi M, Ohta M, Tsukamoto S. Sato I, et al. Among authors: takeuchi m. Bioorg Med Chem. 2008 Jan 1;16(1):144-56. doi: 10.1016/j.bmc.2007.10.003. Epub 2007 Oct 5. Bioorg Med Chem. 2008. PMID: 17951061
Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors.
Nagashima S, Nagata H, Iwata M, Yokota M, Moritomo H, Orita M, Kuromitsu S, Koakutsu A, Ohga K, Takeuchi M, Ohta M, Tsukamoto S. Nagashima S, et al. Among authors: takeuchi m. Bioorg Med Chem. 2008 Jul 1;16(13):6509-21. doi: 10.1016/j.bmc.2008.05.031. Epub 2008 May 17. Bioorg Med Chem. 2008. PMID: 18534856
Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors.
Nagashima S, Hondo T, Nagata H, Ogiyama T, Maeda J, Hoshii H, Kontani T, Kuromitsu S, Ohga K, Orita M, Ohno K, Moritomo A, Shiozuka K, Furutani M, Takeuchi M, Ohta M, Tsukamoto S. Nagashima S, et al. Among authors: takeuchi m. Bioorg Med Chem. 2009 Oct 1;17(19):6926-36. doi: 10.1016/j.bmc.2009.08.021. Epub 2009 Aug 15. Bioorg Med Chem. 2009. PMID: 19747833
Discovery of Ipragliflozin (ASP1941): a novel C-glucoside with benzothiophene structure as a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus.
Imamura M, Nakanishi K, Suzuki T, Ikegai K, Shiraki R, Ogiyama T, Murakami T, Kurosaki E, Noda A, Kobayashi Y, Yokota M, Koide T, Kosakai K, Ohkura Y, Takeuchi M, Tomiyama H, Ohta M. Imamura M, et al. Among authors: takeuchi m. Bioorg Med Chem. 2012 May 15;20(10):3263-79. doi: 10.1016/j.bmc.2012.03.051. Epub 2012 Mar 29. Bioorg Med Chem. 2012. PMID: 22507206
Orally available pyridinylpyrimidine derivatives as novel RANKL-induced osteoclastogenesis inhibitors.
Miyata J, Kasahara C, Asano T, Ito S, Seki N, Kato Y, Morikawa N, Nozaki K, Nishimura K, Akamatsu H, Taguchi Y, Yamaguchi T, Abe Y, Ohkubo M, Watanabe T, Ohta M, Takeuchi M. Miyata J, et al. Among authors: takeuchi m. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5681-4. doi: 10.1016/j.bmcl.2012.06.087. Epub 2012 Jul 6. Bioorg Med Chem Lett. 2012. PMID: 22853997
4,478 results