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Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape.
Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL, Tangsombatvisit S, Grosso JF, Netto G, Smeltzer MP, Chaux A, Utz PJ, Workman CJ, Pardoll DM, Korman AJ, Drake CG, Vignali DA. Woo SR, et al. Among authors: pardoll dm. Cancer Res. 2012 Feb 15;72(4):917-27. doi: 10.1158/0008-5472.CAN-11-1620. Epub 2011 Dec 20. Cancer Res. 2012. PMID: 22186141 Free PMC article.
Role of LAG-3 in regulatory T cells.
Huang CT, Workman CJ, Flies D, Pan X, Marson AL, Zhou G, Hipkiss EL, Ravi S, Kowalski J, Levitsky HI, Powell JD, Pardoll DM, Drake CG, Vignali DA. Huang CT, et al. Among authors: pardoll dm. Immunity. 2004 Oct;21(4):503-13. doi: 10.1016/j.immuni.2004.08.010. Immunity. 2004. PMID: 15485628 Free article.
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.
Drake CG, Doody AD, Mihalyo MA, Huang CT, Kelleher E, Ravi S, Hipkiss EL, Flies DB, Kennedy EP, Long M, McGary PW, Coryell L, Nelson WG, Pardoll DM, Adler AJ. Drake CG, et al. Among authors: pardoll dm. Cancer Cell. 2005 Mar;7(3):239-49. doi: 10.1016/j.ccr.2005.01.027. Cancer Cell. 2005. PMID: 15766662 Free PMC article.
Mechanisms of immune evasion by tumors.
Drake CG, Jaffee E, Pardoll DM. Drake CG, et al. Among authors: pardoll dm. Adv Immunol. 2006;90:51-81. doi: 10.1016/S0065-2776(06)90002-9. Adv Immunol. 2006. PMID: 16730261 Review.
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells.
Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, Grosso JF, Harris TJ, Getnet D, Whartenby KA, Brockstedt DG, Dubensky TW Jr, Chen L, Pardoll DM, Drake CG. Goldberg MV, et al. Among authors: pardoll dm. Blood. 2007 Jul 1;110(1):186-92. doi: 10.1182/blood-2006-12-062422. Epub 2007 Mar 28. Blood. 2007. PMID: 17392506 Free PMC article.
450 results