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BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure.
Singh KK, Shukla PC, Quan A, Desjardins JF, Lovren F, Pan Y, Garg V, Gosal S, Garg A, Szmitko PE, Schneider MD, Parker TG, Stanford WL, Leong-Poi H, Teoh H, Al-Omran M, Verma S. Singh KK, et al. Among authors: shukla pc. J Biol Chem. 2012 Feb 24;287(9):6604-14. doi: 10.1074/jbc.M111.292664. Epub 2011 Dec 8. J Biol Chem. 2012. PMID: 22157755 Free PMC article.
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.
Lovren F, Pan Y, Quan A, Teoh H, Wang G, Shukla PC, Levitt KS, Oudit GY, Al-Omran M, Stewart DJ, Slutsky AS, Peterson MD, Backx PH, Penninger JM, Verma S. Lovren F, et al. Among authors: shukla pc. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1377-84. doi: 10.1152/ajpheart.00331.2008. Epub 2008 Jul 25. Am J Physiol Heart Circ Physiol. 2008. PMID: 18660448 Free article.
DNA damage repair and cardiovascular diseases.
Shukla PC, Singh KK, Yanagawa B, Teoh H, Verma S. Shukla PC, et al. Can J Cardiol. 2010 Mar;26 Suppl A:13A-16A. doi: 10.1016/s0828-282x(10)71055-2. Can J Cardiol. 2010. PMID: 20386754 Review.
Adropin is a novel regulator of endothelial function.
Lovren F, Pan Y, Quan A, Singh KK, Shukla PC, Gupta M, Al-Omran M, Teoh H, Verma S. Lovren F, et al. Among authors: shukla pc. Circulation. 2010 Sep 14;122(11 Suppl):S185-92. doi: 10.1161/CIRCULATIONAHA.109.931782. Circulation. 2010. PMID: 20837912
miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis.
Yanagawa B, Lovren F, Pan Y, Garg V, Quan A, Tang G, Singh KK, Shukla PC, Kalra NP, Peterson MD, Verma S. Yanagawa B, et al. Among authors: shukla pc. J Thorac Cardiovasc Surg. 2012 Jul;144(1):256-62. doi: 10.1016/j.jtcvs.2011.10.097. Epub 2012 Feb 14. J Thorac Cardiovasc Surg. 2012. PMID: 22336757 Free article.
BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis.
Singh KK, Shukla PC, Quan A, Al-Omran M, Lovren F, Pan Y, Brezden-Masley C, Ingram AJ, Stanford WL, Teoh H, Verma S. Singh KK, et al. Among authors: shukla pc. J Thorac Cardiovasc Surg. 2013 Oct;146(4):949-960.e4. doi: 10.1016/j.jtcvs.2012.12.064. Epub 2013 Feb 14. J Thorac Cardiovasc Surg. 2013. PMID: 23415688 Free article.
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