Imanishi T - Search Results

1

Cleavage of oligonucleotides containing a P3'→N5' phosphoramidate linkage mediated by single-stranded oligonucleotide templates.

Ito KR, Kodama T, Makimura F, Hosoki N, Osaki T, Orita A, Imanishi T, Obika S. Ito KR, et al. Among authors: imanishi t. Molecules. 2011 Dec 20;16(12):10695-708. doi: 10.3390/molecules161210695. Molecules. 2011. PMID: 22186956 Free PMC article.

2

Synthesis and properties of 5'-amino-2',4'-BNA modified oligonucleotides with P3'-->N5' phosphoramidate linkages.

Obika S, Nakagawa O, Hiroto A, Hari Y, Imanishi T. Obika S, et al. Among authors: imanishi t. Nucleic Acids Res Suppl. 2002;(2):25-6. doi: 10.1093/nass/2.1.25. Nucleic Acids Res Suppl. 2002. PMID: 12903087

3

A novel nucleic acid analogue, 3'-amino-2'-deoxy-3',4'-BNA, with an N3'-->P5' phosphoramidate linkage and an S-type conformation.

Nakagawa O, Hiroto A, Obika S, Imanishi T. Nakagawa O, et al. Among authors: imanishi t. Nucleic Acids Res Suppl. 2003;(3):87-8. doi: 10.1093/nass/3.1.87. Nucleic Acids Res Suppl. 2003. PMID: 14510393

4

Synthesis and properties of a novel bridged nucleic acid analogue bearing a P3'-->N5' phosphoroamidate linkage, 5'-amino-3', 5'-BNA.

Sekiguchi M, Obika S, Somjing R, Imanishi T. Sekiguchi M, et al. Among authors: imanishi t. Nucleic Acids Symp Ser (Oxf). 2004;(48):7-8. doi: 10.1093/nass/48.1.7. Nucleic Acids Symp Ser (Oxf). 2004. PMID: 17150451

5

Promotion of acid-mediated cleavage of oligonucleotide P3'->N5' phosphoroamidates by triplex formation: a novel approach to sequence-specific DNA detection.

Tomizu M, Nakagawa O, Obika S, Imanishi T. Tomizu M, et al. Among authors: imanishi t. Nucleic Acids Symp Ser (Oxf). 2005;(49):157-8. doi: 10.1093/nass/49.1.157. Nucleic Acids Symp Ser (Oxf). 2005. PMID: 17150681

6

Acid-mediated cleavage of oligonucleotide P3' --> N5' phosphoramidates triggered by sequence-specific triplex formation.

Obika S, Tomizu M, Negoro Y, Osaki T, Orita A, Ueyama Y, Nakagawa O, Imanishi T. Obika S, et al. Among authors: imanishi t. Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):893-6. doi: 10.1080/15257770701505741. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18058503

7

Double-stranded DNA-templated cleavage of oligonucleotides containing a P3'->N5' linkage triggered by triplex formation: the effects of chemical modifications and remarkable enhancement in reactivity.

Ito KR, Kodama T, Tomizu M, Negoro Y, Orita A, Osaki T, Hosoki N, Tanaka T, Imanishi T, Obika S. Ito KR, et al. Among authors: imanishi t. Nucleic Acids Res. 2010 Nov;38(20):7332-42. doi: 10.1093/nar/gkq600. Epub 2010 Jul 8. Nucleic Acids Res. 2010. PMID: 20615902 Free PMC article.

8

[Down-regulation of a gene-expression by an antisense BNA oligonucleotide].

Imanishi T, Obika S. Imanishi T, et al. Nihon Yakurigaku Zasshi. 2002 Aug;120(2):85-90. doi: 10.1254/fpj.120.85. Nihon Yakurigaku Zasshi. 2002. PMID: 12187626 Review. Japanese.

9

BNAs: novel nucleic acid analogs with a bridged sugar moiety.

Imanishi T, Obika S. Imanishi T, et al. Chem Commun (Camb). 2002 Aug 21;(16):1653-9. doi: 10.1039/b201557a. Chem Commun (Camb). 2002. PMID: 12196936 Review.

10

Stable oligonucleotide-directed triplex formation at target sites with CG interruptions: strong sequence-specific recognition by 2',4'-bridged nucleic-acid-containing 2-pyridones under physiological conditions.

Obika S, Hari Y, Sekiguchi M, Imanishi T. Obika S, et al. Among authors: imanishi t. Chemistry. 2002 Oct 18;8(20):4796-802. doi: 10.1002/1521-3765(20021018)8:20<4796::AID-CHEM4796>3.0.CO;2-O. Chemistry. 2002. PMID: 12561120

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