Man S - Search Results

1

Low-dose metronomic oral dosing of a prodrug of gemcitabine (LY2334737) causes antitumor effects in the absence of inhibition of systemic vasculogenesis.

Francia G, Shaked Y, Hashimoto K, Sun J, Yin M, Cesta C, Xu P, Man S, Hackl C, Stewart J, Uhlik M, Dantzig AH, Foster FS, Kerbel RS. Francia G, et al. Among authors: man s. Mol Cancer Ther. 2012 Mar;11(3):680-9. doi: 10.1158/1535-7163.MCT-11-0659. Epub 2011 Dec 21. Mol Cancer Ther. 2012. PMID: 22188817 Free PMC article.

2

Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.

Man S, Bocci G, Francia G, Green SK, Jothy S, Hanahan D, Bohlen P, Hicklin DJ, Bergers G, Kerbel RS. Man S, et al. Cancer Res. 2002 May 15;62(10):2731-5. Cancer Res. 2002. PMID: 12019144

3

Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy.

Bocci G, Francia G, Man S, Lawler J, Kerbel RS. Bocci G, et al. Among authors: man s. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12917-22. doi: 10.1073/pnas.2135406100. Epub 2003 Oct 15. Proc Natl Acad Sci U S A. 2003. PMID: 14561896 Free PMC article.

4

A comparative analysis of low-dose metronomic cyclophosphamide reveals absent or low-grade toxicity on tissues highly sensitive to the toxic effects of maximum tolerated dose regimens.

Emmenegger U, Man S, Shaked Y, Francia G, Wong JW, Hicklin DJ, Kerbel RS. Emmenegger U, et al. Among authors: man s. Cancer Res. 2004 Jun 1;64(11):3994-4000. doi: 10.1158/0008-5472.CAN-04-0580. Cancer Res. 2004. PMID: 15173013

5

Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity.

Shaked Y, Emmenegger U, Man S, Cervi D, Bertolini F, Ben-David Y, Kerbel RS. Shaked Y, et al. Among authors: man s. Blood. 2005 Nov 1;106(9):3058-61. doi: 10.1182/blood-2005-04-1422. Epub 2005 Jul 5. Blood. 2005. PMID: 15998832 Free PMC article.

6

Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy.

Shaked Y, Emmenegger U, Francia G, Chen L, Lee CR, Man S, Paraghamian A, Ben-David Y, Kerbel RS. Shaked Y, et al. Among authors: man s. Cancer Res. 2005 Aug 15;65(16):7045-51. doi: 10.1158/0008-5472.CAN-05-0765. Cancer Res. 2005. PMID: 16103050

7

Anti-angiogenic treatment of breast cancer using metronomic low-dose chemotherapy.

Munoz R, Shaked Y, Bertolini F, Emmenegger U, Man S, Kerbel RS. Munoz R, et al. Among authors: man s. Breast. 2005 Dec;14(6):466-79. doi: 10.1016/j.breast.2005.08.026. Epub 2005 Sep 30. Breast. 2005. PMID: 16199161 Review.

8

Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents.

Francia G, Green SK, Bocci G, Man S, Emmenegger U, Ebos JM, Weinerman A, Shaked Y, Kerbel RS. Francia G, et al. Among authors: man s. Mol Cancer Ther. 2005 Oct;4(10):1484-94. doi: 10.1158/1535-7163.MCT-04-0214. Mol Cancer Ther. 2005. PMID: 16227397

9

Low-dose metronomic daily cyclophosphamide and weekly tirapazamine: a well-tolerated combination regimen with enhanced efficacy that exploits tumor hypoxia.

Emmenegger U, Morton GC, Francia G, Shaked Y, Franco M, Weinerman A, Man S, Kerbel RS. Emmenegger U, et al. Among authors: man s. Cancer Res. 2006 Feb 1;66(3):1664-74. doi: 10.1158/0008-5472.CAN-05-2598. Cancer Res. 2006. PMID: 16452226

10

Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT-cyclophosphamide metronomic chemotherapy.

Munoz R, Man S, Shaked Y, Lee CR, Wong J, Francia G, Kerbel RS. Munoz R, et al. Among authors: man s. Cancer Res. 2006 Apr 1;66(7):3386-91. doi: 10.1158/0008-5472.CAN-05-4411. Cancer Res. 2006. PMID: 16585158

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