Handel T - Search Results

1

Heparin-induced leukocytosis requires 6-O-sulfation and is caused by blockade of selectin- and CXCL12 protein-mediated leukocyte trafficking in mice.

Zhang S, Condac E, Qiu H, Jiang J, Gutierrez-Sanchez G, Bergmann C, Handel T, Wang L. Zhang S, et al. Among authors: handel t. J Biol Chem. 2012 Feb 17;287(8):5542-53. doi: 10.1074/jbc.M111.314716. Epub 2011 Dec 22. J Biol Chem. 2012. PMID: 22194593 Free PMC article.

2

Monomeric monocyte chemoattractant protein-1 (MCP-1) binds and activates the MCP-1 receptor CCR2B.

Paavola CD, Hemmerich S, Grunberger D, Polsky I, Bloom A, Freedman R, Mulkins M, Bhakta S, McCarley D, Wiesent L, Wong B, Jarnagin K, Handel TM. Paavola CD, et al. Among authors: handel tm. J Biol Chem. 1998 Dec 11;273(50):33157-65. doi: 10.1074/jbc.273.50.33157. J Biol Chem. 1998. PMID: 9837883 Free article.

3

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

Lau EK, Paavola CD, Johnson Z, Gaudry JP, Geretti E, Borlat F, Kungl AJ, Proudfoot AE, Handel TM. Lau EK, et al. J Biol Chem. 2004 May 21;279(21):22294-305. doi: 10.1074/jbc.M311224200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15033992 Free article.

4

Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.

Mizoue LS, Sullivan SK, King DS, Kledal TN, Schwartz TW, Bacon KB, Handel TM. Mizoue LS, et al. Among authors: handel tm. J Biol Chem. 2001 Sep 7;276(36):33906-14. doi: 10.1074/jbc.M101348200. Epub 2001 Jun 29. J Biol Chem. 2001. PMID: 11432858 Free article.

5

Heterodimerization of CCR2 chemokines and regulation by glycosaminoglycan binding.

Crown SE, Yu Y, Sweeney MD, Leary JA, Handel TM. Crown SE, et al. J Biol Chem. 2006 Sep 1;281(35):25438-46. doi: 10.1074/jbc.M601518200. Epub 2006 Jun 27. J Biol Chem. 2006. PMID: 16803905 Free article.

6

Dual targeting of the chemokine receptors CXCR4 and ACKR3 with novel engineered chemokines.

Hanes MS, Salanga CL, Chowdry AB, Comerford I, McColl SR, Kufareva I, Handel TM. Hanes MS, et al. J Biol Chem. 2015 Sep 11;290(37):22385-97. doi: 10.1074/jbc.M115.675108. Epub 2015 Jul 27. J Biol Chem. 2015. PMID: 26216880 Free PMC article.

7

Heparan Sulfate Microarray Reveals That Heparan Sulfate-Protein Binding Exhibits Different Ligand Requirements.

Zong C, Venot A, Li X, Lu W, Xiao W, Wilkes JL, Salanga CL, Handel TM, Wang L, Wolfert MA, Boons GJ. Zong C, et al. J Am Chem Soc. 2017 Jul 19;139(28):9534-9543. doi: 10.1021/jacs.7b01399. Epub 2017 Jul 7. J Am Chem Soc. 2017. PMID: 28651046 Free PMC article.

8

Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t.

Ward RJ, Pediani JD, Marsango S, Jolly R, Stoneman MR, Biener G, Handel TM, Raicu V, Milligan G. Ward RJ, et al. J Biol Chem. 2021 Jan-Jun;296:100139. doi: 10.1074/jbc.RA120.016612. Epub 2020 Dec 6. J Biol Chem. 2021. PMID: 33268380 Free PMC article.

9

The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement.

Hoover DM, Mizoue LS, Handel TM, Lubkowski J. Hoover DM, et al. Among authors: handel tm. J Biol Chem. 2000 Jul 28;275(30):23187-93. doi: 10.1074/jbc.M002584200. J Biol Chem. 2000. PMID: 10770945 Free article.

10

Chemokine-receptor interactions: GPCRs, glycosaminoglycans and viral chemokine binding proteins.

Lau EK, Allen S, Hsu AR, Handel TM. Lau EK, et al. Adv Protein Chem. 2004;68:351-91. doi: 10.1016/S0065-3233(04)68010-7. Adv Protein Chem. 2004. PMID: 15500866 Review.

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