Schlacher K - Search Results

1

Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.

Siaud N, Barbera MA, Egashira A, Lam I, Christ N, Schlacher K, Xia B, Jasin M. Siaud N, et al. Among authors: schlacher k. PLoS Genet. 2011 Dec;7(12):e1002409. doi: 10.1371/journal.pgen.1002409. Epub 2011 Dec 15. PLoS Genet. 2011. PMID: 22194698 Free PMC article.

2

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M. Schlacher K, et al. Cell. 2011 May 13;145(4):529-42. doi: 10.1016/j.cell.2011.03.041. Cell. 2011. PMID: 21565612 Free PMC article.

3

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

Schlacher K, Wu H, Jasin M. Schlacher K, et al. Cancer Cell. 2012 Jul 10;22(1):106-16. doi: 10.1016/j.ccr.2012.05.015. Cancer Cell. 2012. PMID: 22789542 Free PMC article.

4

p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways.

Roy S, Tomaszowski KH, Luzwick JW, Park S, Li J, Murphy M, Schlacher K. Roy S, et al. Among authors: schlacher k. Elife. 2018 Jan 15;7:e31723. doi: 10.7554/eLife.31723. Elife. 2018. PMID: 29334356 Free PMC article.

5

SIRF: Quantitative in situ analysis of protein interactions at DNA replication forks.

Roy S, Luzwick JW, Schlacher K. Roy S, et al. Among authors: schlacher k. J Cell Biol. 2018 Apr 2;217(4):1521-1536. doi: 10.1083/jcb.201709121. Epub 2018 Feb 23. J Cell Biol. 2018. PMID: 29475976 Free PMC article.

6

Interaction of Chk1 with Treslin negatively regulates the initiation of chromosomal DNA replication.

Guo C, Kumagai A, Schlacher K, Shevchenko A, Shevchenko A, Dunphy WG. Guo C, et al. Among authors: schlacher k. Mol Cell. 2015 Feb 5;57(3):492-505. doi: 10.1016/j.molcel.2014.12.003. Epub 2014 Dec 31. Mol Cell. 2015. PMID: 25557548 Free PMC article.

7

Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.

Xu S, Wu X, Wu L, Castillo A, Liu J, Atkinson E, Paul A, Su D, Schlacher K, Komatsu Y, You MJ, Wang B. Xu S, et al. Among authors: schlacher k. Genes Dev. 2017 Jul 15;31(14):1469-1482. doi: 10.1101/gad.299172.117. Genes Dev. 2017. PMID: 28860160 Free PMC article.

8

Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress.

Tomaszowski KH, Roy S, Guerrero C, Shukla P, Keshvani C, Chen Y, Ott M, Wu X, Zhang J, DiNardo CD, Schindler D, Schlacher K. Tomaszowski KH, et al. Among authors: schlacher k. Nat Commun. 2023 Mar 11;14(1):1333. doi: 10.1038/s41467-023-36933-y. Nat Commun. 2023. PMID: 36906610 Free PMC article.

9

RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles.

Longo MA, Roy S, Chen Y, Tomaszowski KH, Arvai AS, Pepper JT, Boisvert RA, Kunnimalaiyaan S, Keshvani C, Schild D, Bacolla A, Williams GJ, Tainer JA, Schlacher K. Longo MA, et al. Among authors: schlacher k. Nat Commun. 2023 Jul 24;14(1):4445. doi: 10.1038/s41467-023-40096-1. Nat Commun. 2023. PMID: 37488098 Free PMC article.

10

Constitutive role of the Fanconi anemia D2 gene in the replication stress response.

Tian Y, Shen X, Wang R, Klages-Mundt NL, Lynn EJ, Martin SK, Ye Y, Gao M, Chen J, Schlacher K, Li L. Tian Y, et al. Among authors: schlacher k. J Biol Chem. 2017 Dec 8;292(49):20184-20195. doi: 10.1074/jbc.M117.814780. Epub 2017 Oct 11. J Biol Chem. 2017. PMID: 29021208 Free PMC article.

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