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Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation.
Fernandez PL, Dutra FF, Alves L, Figueiredo RT, Mourão-Sa D, Fortes GB, Bergstrand S, Lönn D, Cevallos RR, Pereira RMS, Lopes UG, Travassos LH, Paiva CN, Bozza MT. Fernandez PL, et al. Among authors: figueiredo rt. J Biol Chem. 2010 Oct 22;285(43):32844-32851. doi: 10.1074/jbc.M110.146076. Epub 2010 Aug 20. J Biol Chem. 2010. PMID: 20729208 Free PMC article.
TLR4 recognizes Pseudallescheria boydii conidia and purified rhamnomannans.
Figueiredo RT, Fernandez PL, Dutra FF, González Y, Lopes LC, Bittencourt VC, Sassaki GL, Barreto-Bergter E, Bozza MT. Figueiredo RT, et al. J Biol Chem. 2010 Dec 24;285(52):40714-23. doi: 10.1074/jbc.M110.181255. Epub 2010 Oct 19. J Biol Chem. 2010. PMID: 20959459 Free PMC article.
Glycoconjugates and polysaccharides from the Scedosporium/Pseudallescheria boydii complex: structural characterisation, involvement in cell differentiation, cell recognition and virulence.
Lopes LC, da Silva MI, Bittencourt VC, Figueiredo RT, Rollin-Pinheiro R, Sassaki GL, Bozza MT, Gorin PA, Barreto-Bergter E. Lopes LC, et al. Among authors: figueiredo rt. Mycoses. 2011 Oct;54 Suppl 3:28-36. doi: 10.1111/j.1439-0507.2011.02105.x. Mycoses. 2011. PMID: 21995660 Review.
Characterization of heme as activator of Toll-like receptor 4.
Figueiredo RT, Fernandez PL, Mourao-Sa DS, Porto BN, Dutra FF, Alves LS, Oliveira MF, Oliveira PL, Graça-Souza AV, Bozza MT. Figueiredo RT, et al. J Biol Chem. 2007 Jul 13;282(28):20221-9. doi: 10.1074/jbc.M610737200. Epub 2007 May 14. J Biol Chem. 2007. PMID: 17502383 Free article.
Trypanosoma cruzi infection is enhanced by vector saliva through immunosuppressant mechanisms mediated by lysophosphatidylcholine.
Mesquita RD, Carneiro AB, Bafica A, Gazos-Lopes F, Takiya CM, Souto-Padron T, Vieira DP, Ferreira-Pereira A, Almeida IC, Figueiredo RT, Porto BN, Bozza MT, Graça-Souza AV, Lopes AH, Atella GC, Silva-Neto MA. Mesquita RD, et al. Among authors: figueiredo rt. Infect Immun. 2008 Dec;76(12):5543-52. doi: 10.1128/IAI.00683-08. Epub 2008 Sep 15. Infect Immun. 2008. PMID: 18794282 Free PMC article.
Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration.
Rozenfeld C, Martinez R, Figueiredo RT, Bozza MT, Lima FR, Pires AL, Silva PM, Bonomo A, Lannes-Vieira J, De Souza W, Moura-Neto V. Rozenfeld C, et al. Among authors: figueiredo rt. Infect Immun. 2003 Apr;71(4):2047-57. doi: 10.1128/IAI.71.4.2047-2057.2003. Infect Immun. 2003. PMID: 12654825 Free PMC article.
40 results