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Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention.
Rodriguez GC, Turbov J, Rosales R, Yoo J, Hunn J, Zappia KJ, Lund K, Barry CP, Rodriguez IV, Pike JW, Conrads TP, Darcy KM, Maxwell GL, Hamilton CA, Syed V, Thaete LG. Rodriguez GC, et al. Among authors: thaete lg. Gynecol Oncol. 2016 Oct;143(1):159-167. doi: 10.1016/j.ygyno.2016.04.022. Epub 2016 Jul 29. Gynecol Oncol. 2016. PMID: 27106018
Phase II Trial of Chemopreventive Effects of Levonorgestrel on Ovarian and Fallopian Tube Epithelium in Women at High Risk for Ovarian Cancer: An NRG Oncology Group/GOG Study.
Rodriguez GC, Kauderer J, Hunn J, Thaete LG, Watkin WG, Russell S, Yozwiak M, Basil J, Hurteau J, Lele S, Modesitt SC, Zivanovic O, Zhang HH, Bartels PH, Alberts DS. Rodriguez GC, et al. Among authors: thaete lg. Cancer Prev Res (Phila). 2019 Jun;12(6):401-412. doi: 10.1158/1940-6207.CAPR-18-0383. Epub 2019 Apr 23. Cancer Prev Res (Phila). 2019. PMID: 31015198 Free PMC article. Clinical Trial.
Progesterone enhances calcitriol antitumor activity by upregulating vitamin D receptor expression and promoting apoptosis in endometrial cancer cells.
Lee LR, Teng PN, Nguyen H, Hood BL, Kavandi L, Wang G, Turbov JM, Thaete LG, Hamilton CA, Maxwell GL, Rodriguez GC, Conrads TP, Syed V. Lee LR, et al. Among authors: thaete lg. Cancer Prev Res (Phila). 2013 Jul;6(7):731-43. doi: 10.1158/1940-6207.CAPR-12-0493. Epub 2013 May 16. Cancer Prev Res (Phila). 2013. PMID: 23682076
55 results