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Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series.
Lachance N, Gareau Y, Guiral S, Huang Z, Isabel E, Leclerc JP, Léger S, Martins E, Nadeau C, Oballa RM, Ouellet SG, Powell DA, Ramtohul YK, Tranmer GK, Trinh T, Wang H, Zhang L. Lachance N, et al. Among authors: nadeau c. Bioorg Med Chem Lett. 2012 Jan 15;22(2):980-4. doi: 10.1016/j.bmcl.2011.12.002. Epub 2011 Dec 8. Bioorg Med Chem Lett. 2012. PMID: 22209206
Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Bungard CJ, Williams PD, Ballard JE, Bennett DJ, Beaulieu C, Bahnck-Teets C, Carroll SS, Chang RK, Dubost DC, Fay JF, Diamond TL, Greshock TJ, Hao L, Holloway MK, Felock PJ, Gesell JJ, Su HP, Manikowski JJ, McKay DJ, Miller M, Min X, Molinaro C, Moradei OM, Nantermet PG, Nadeau C, Sanchez RI, Satyanarayana T, Shipe WD, Singh SK, Truong VL, Vijayasaradhi S, Wiscount CM, Vacca JP, Crane SN, McCauley JA. Bungard CJ, et al. Among authors: nadeau c. ACS Med Chem Lett. 2016 May 9;7(7):702-7. doi: 10.1021/acsmedchemlett.6b00135. eCollection 2016 Jul 14. ACS Med Chem Lett. 2016. PMID: 27437081 Free PMC article.
A practical synthesis of 5-lipoxygenase inhibitor MK-0633.
Gosselin F, Britton RA, Davies IW, Dolman SJ, Gauvreau D, Hoerrner RS, Hughes G, Janey J, Lau S, Molinaro C, Nadeau C, O'Shea PD, Palucki M, Sidler R. Gosselin F, et al. Among authors: nadeau c. J Org Chem. 2010 Jun 18;75(12):4154-60. doi: 10.1021/jo100561u. J Org Chem. 2010. PMID: 20486715
Point of Care Ultrasonography for the Evaluation of Ocular Emergencies.
Gonzalez JM, Ortega J, Snowden K, Larrieu-Jimenez P, Crenshaw N, Nadeau C, McGhee S. Gonzalez JM, et al. Among authors: nadeau c. Adv Emerg Nurs J. 2024 Dec 6. doi: 10.1097/TME.0000000000000549. Online ahead of print. Adv Emerg Nurs J. 2024. PMID: 39641540
Synthetic datasets can provide the health service with better AI models.
Vallevik VB, Befring AKC, Brøgger HMB, Nadeau C. Vallevik VB, et al. Among authors: nadeau c. Tidsskr Nor Laegeforen. 2024 Nov 11;144(14). doi: 10.4045/tidsskr.24.0328. Print 2024 Nov 26. Tidsskr Nor Laegeforen. 2024. PMID: 39605144 Free article. English, Norwegian. No abstract available.
155 results