Leal PC - Search Results

1

Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation.

Mielcke TR, Mascarello A, Filippi-Chiela E, Zanin RF, Lenz G, Leal PC, Chiaradia LD, Yunes RA, Nunes RJ, Battastini AM, Morrone FB, Campos MM. Mielcke TR, et al. Among authors: leal pc. Eur J Med Chem. 2012 Feb;48:255-64. doi: 10.1016/j.ejmech.2011.12.023. Epub 2011 Dec 22. Eur J Med Chem. 2012. PMID: 22209415

2

Synthesis and pharmacological activity of chalcones derived from 2,4,6-trimethoxyacetophenone in RAW 264.7 cells stimulated by LPS: quantitative structure-activity relationships.

Chiaradia LD, dos Santos R, Vitor CE, Vieira AA, Leal PC, Nunes RJ, Calixto JB, Yunes RA. Chiaradia LD, et al. Among authors: leal pc. Bioorg Med Chem. 2008 Jan 15;16(2):658-67. doi: 10.1016/j.bmc.2007.10.039. Epub 2007 Oct 18. Bioorg Med Chem. 2008. PMID: 17988874

3

In vitro and in vivo anti-glioma activity of a chalcone-quinoxaline hybrid.

Loch-Neckel G, Bicca MA, Leal PC, Mascarello A, Siqueira JM, Calixto JB. Loch-Neckel G, et al. Among authors: leal pc. Eur J Med Chem. 2015 Jan 27;90:93-100. doi: 10.1016/j.ejmech.2014.11.014. Epub 2014 Nov 6. Eur J Med Chem. 2015. PMID: 25461314

4

Inhibition of phosphatidylinositol-3 kinase γ reduces pruriceptive, inflammatory, and nociceptive responses induced by trypsin in mice.

Pereira PJS, Lazarotto LF, Leal PC, Lopes TG, Morrone FB, Campos MM. Pereira PJS, et al. Among authors: leal pc. Pain. 2011 Dec;152(12):2861-2869. doi: 10.1016/j.pain.2011.09.016. Epub 2011 Oct 15. Pain. 2011. PMID: 22001656

5

Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position.

Winter E, Gozzi GJ, Chiaradia-Delatorre LD, Daflon-Yunes N, Terreux R, Gauthier C, Mascarello A, Leal PC, Cadena SM, Yunes RA, Nunes RJ, Creczynski-Pasa TB, Di Pietro A. Winter E, et al. Among authors: leal pc. Drug Des Devel Ther. 2014 May 27;8:609-19. doi: 10.2147/DDDT.S56625. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 24920885 Free PMC article.

6

Relationship between the lipophilicity of gallic acid n-alquil esters' derivatives and both myeloperoxidase activity and HOCl scavenging.

Rosso R, Vieira TO, Leal PC, Nunes RJ, Yunes RA, Creczynski-Pasa TB. Rosso R, et al. Among authors: leal pc. Bioorg Med Chem. 2006 Sep 15;14(18):6409-13. doi: 10.1016/j.bmc.2006.05.038. Epub 2006 Jun 8. Bioorg Med Chem. 2006. PMID: 16759870

7

The role of CXCR2 chemokine receptors in the oral squamous cell carcinoma.

Romanini J, Mielcke TR, Leal PC, Figueiredo CP, Calixto JB, Morrone FB, Batista EL Jr, Campos MM. Romanini J, et al. Among authors: leal pc. Invest New Drugs. 2012 Aug;30(4):1371-8. doi: 10.1007/s10637-011-9701-x. Epub 2011 Jun 14. Invest New Drugs. 2012. PMID: 21670971

8

N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.

Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. Salum LB, et al. Among authors: leal pc. Eur J Med Chem. 2015;96:504-18. doi: 10.1016/j.ejmech.2015.02.041. Epub 2015 Feb 23. Eur J Med Chem. 2015. PMID: 25951294

9

Relation between lipophilicity of alkyl gallates and antifungal activity against yeasts and filamentous fungi.

Leal PC, Mascarello A, Derita M, Zuljan F, Nunes RJ, Zacchino S, Yunes RA. Leal PC, et al. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1793-6. doi: 10.1016/j.bmcl.2009.01.061. Epub 2009 Jan 27. Bioorg Med Chem Lett. 2009. PMID: 19232493

10

Influence of chalcone analogues on serum glucose levels in hyperglycemic rats.

Alberton EH, Damazio RG, Cazarolli LH, Chiaradia LD, Leal PC, Nunes RJ, Yunes RA, Silva FR. Alberton EH, et al. Among authors: leal pc. Chem Biol Interact. 2008 Feb 15;171(3):355-62. doi: 10.1016/j.cbi.2007.11.001. Epub 2007 Nov 17. Chem Biol Interact. 2008. PMID: 18164698

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