Figg N - Search Results

1

The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice.

Mercer JR, Yu E, Figg N, Cheng KK, Prime TA, Griffin JL, Masoodi M, Vidal-Puig A, Murphy MP, Bennett MR. Mercer JR, et al. Among authors: figg n. Free Radic Biol Med. 2012 Mar 1;52(5):841-9. doi: 10.1016/j.freeradbiomed.2011.11.026. Epub 2011 Dec 14. Free Radic Biol Med. 2012. PMID: 22210379

2

Endogenous p53 protects vascular smooth muscle cells from apoptosis and reduces atherosclerosis in ApoE knockout mice.

Mercer J, Figg N, Stoneman V, Braganza D, Bennett MR. Mercer J, et al. Among authors: figg n. Circ Res. 2005 Apr 1;96(6):667-74. doi: 10.1161/01.RES.0000161069.15577.ca. Epub 2005 Mar 3. Circ Res. 2005. PMID: 15746445

3

Interferon-gamma induces Fas trafficking and sensitization to apoptosis in vascular smooth muscle cells via a PI3K- and Akt-dependent mechanism.

Rosner D, Stoneman V, Littlewood T, McCarthy N, Figg N, Wang Y, Tellides G, Bennett M. Rosner D, et al. Among authors: figg n. Am J Pathol. 2006 Jun;168(6):2054-63. doi: 10.2353/ajpath.2006.050473. Am J Pathol. 2006. PMID: 16723718 Free PMC article.

4

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.

Clarke MC, Figg N, Maguire JJ, Davenport AP, Goddard M, Littlewood TD, Bennett MR. Clarke MC, et al. Among authors: figg n. Nat Med. 2006 Sep;12(9):1075-80. doi: 10.1038/nm1459. Epub 2006 Aug 6. Nat Med. 2006. PMID: 16892061

5

Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques.

Stoneman V, Braganza D, Figg N, Mercer J, Lang R, Goddard M, Bennett M. Stoneman V, et al. Among authors: figg n. Circ Res. 2007 Mar 30;100(6):884-93. doi: 10.1161/01.RES.0000260802.75766.00. Epub 2007 Feb 22. Circ Res. 2007. PMID: 17322176 Free PMC article.

6

Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment.

Kavurma MM, Figg N, Bennett MR, Mercer J, Khachigian LM, Littlewood TD. Kavurma MM, et al. Among authors: figg n. Biochem J. 2007 Oct 1;407(1):79-87. doi: 10.1042/BJ20070380. Biochem J. 2007. PMID: 17600529 Free PMC article.

7

Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.

Allard D, Figg N, Bennett MR, Littlewood TD. Allard D, et al. Among authors: figg n. J Biol Chem. 2008 Jul 11;283(28):19739-47. doi: 10.1074/jbc.M710098200. Epub 2008 May 5. J Biol Chem. 2008. PMID: 18458087 Free article.

8

Chronic apoptosis of vascular smooth muscle cells accelerates atherosclerosis and promotes calcification and medial degeneration.

Clarke MC, Littlewood TD, Figg N, Maguire JJ, Davenport AP, Goddard M, Bennett MR. Clarke MC, et al. Among authors: figg n. Circ Res. 2008 Jun 20;102(12):1529-38. doi: 10.1161/CIRCRESAHA.108.175976. Epub 2008 May 22. Circ Res. 2008. PMID: 18497329

9

Vascular smooth muscle cell apoptosis induces interleukin-1-directed inflammation: effects of hyperlipidemia-mediated inhibition of phagocytosis.

Clarke MC, Talib S, Figg NL, Bennett MR. Clarke MC, et al. Circ Res. 2010 Feb 5;106(2):363-72. doi: 10.1161/CIRCRESAHA.109.208389. Epub 2009 Nov 19. Circ Res. 2010. PMID: 19926874

10

High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-kappaB-complex-dependent gene expression in human heart failure.

Choy MK, Movassagh M, Siggens L, Vujic A, Goddard M, Sánchez A, Perkins N, Figg N, Bennett M, Carroll J, Foo R. Choy MK, et al. Among authors: figg n. Genome Med. 2010 Jun 14;2(6):37. doi: 10.1186/gm158. Genome Med. 2010. PMID: 20546595 Free PMC article.

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