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Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.
Wu CH, Coumar MS, Chu CY, Lin WH, Chen YR, Chen CT, Shiao HY, Rafi S, Wang SY, Hsu H, Chen CH, Chang CY, Chang TY, Lien TW, Fang MY, Yeh KC, Chen CP, Yeh TK, Hsieh SH, Hsu JT, Liao CC, Chao YS, Hsieh HP. Wu CH, et al. Among authors: hsu jt, hsu h. J Med Chem. 2010 Oct 28;53(20):7316-26. doi: 10.1021/jm100607r. J Med Chem. 2010. PMID: 20961149
Antiviral drug discovery against SARS-CoV.
Wu YS, Lin WH, Hsu JT, Hsieh HP. Wu YS, et al. Among authors: hsu jt. Curr Med Chem. 2006;13(17):2003-20. doi: 10.2174/092986706777584988. Curr Med Chem. 2006. PMID: 16842194
576 results