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The interaction of PKN3 with RhoC promotes malignant growth.
Unsal-Kacmaz K, Ragunathan S, Rosfjord E, Dann S, Upeslacis E, Grillo M, Hernandez R, Mack F, Klippel A. Unsal-Kacmaz K, et al. Mol Oncol. 2012 Jun;6(3):284-98. doi: 10.1016/j.molonc.2011.12.001. Epub 2011 Dec 28. Mol Oncol. 2012. PMID: 22217540 Free PMC article.
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer.
Kim J, Lee HM, Cai F, Ko B, Yang C, Lieu EL, Muhammad N, Rhyne S, Li K, Haloul M, Gu W, Faubert B, Kaushik AK, Cai L, Kasiri S, Marriam U, Nham K, Girard L, Wang H, Sun X, Kim J, Minna JD, Unsal-Kacmaz K, DeBerardinis RJ. Kim J, et al. Nat Metab. 2020 Dec;2(12):1401-1412. doi: 10.1038/s42255-020-00316-0. Epub 2020 Nov 30. Nat Metab. 2020. PMID: 33257855 Free PMC article.
Preferential binding of ATR protein to UV-damaged DNA.
Unsal-Kaçmaz K, Makhov AM, Griffith JD, Sancar A. Unsal-Kaçmaz K, et al. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6673-8. doi: 10.1073/pnas.102167799. Proc Natl Acad Sci U S A. 2002. PMID: 12011431 Free PMC article.
Cdc7-Dbf4 and the human S checkpoint response to UVC.
Heffernan TP, Ünsal-Kaçmaz K, Heinloth AN, Simpson DA, Paules RS, Sancar A, Cordeiro-Stone M, Kaufmann WK. Heffernan TP, et al. J Biol Chem. 2007 Mar 30;282(13):9458-9468. doi: 10.1074/jbc.M611292200. Epub 2007 Feb 2. J Biol Chem. 2007. PMID: 17276990 Free PMC article.
26 results