van Noort V - Search Results

1

Prediction of drug combinations by integrating molecular and pharmacological data.

Zhao XM, Iskar M, Zeller G, Kuhn M, van Noort V, Bork P. Zhao XM, et al. Among authors: van noort v. PLoS Comput Biol. 2011 Dec;7(12):e1002323. doi: 10.1371/journal.pcbi.1002323. Epub 2011 Dec 29. PLoS Comput Biol. 2011. PMID: 22219721 Free PMC article.

2

Drug-induced regulation of target expression.

Iskar M, Campillos M, Kuhn M, Jensen LJ, van Noort V, Bork P. Iskar M, et al. Among authors: van noort v. PLoS Comput Biol. 2010 Sep 9;6(9):e1000925. doi: 10.1371/journal.pcbi.1000925. PLoS Comput Biol. 2010. PMID: 20838579 Free PMC article.

3

Drug discovery in the age of systems biology: the rise of computational approaches for data integration.

Iskar M, Zeller G, Zhao XM, van Noort V, Bork P. Iskar M, et al. Among authors: van noort v. Curr Opin Biotechnol. 2012 Aug;23(4):609-16. doi: 10.1016/j.copbio.2011.11.010. Epub 2011 Dec 5. Curr Opin Biotechnol. 2012. PMID: 22153034 Review.

4

Network neighbors of drug targets contribute to drug side-effect similarity.

Brouwers L, Iskar M, Zeller G, van Noort V, Bork P. Brouwers L, et al. Among authors: van noort v. PLoS One. 2011;6(7):e22187. doi: 10.1371/journal.pone.0022187. Epub 2011 Jul 13. PLoS One. 2011. PMID: 21765950 Free PMC article.

5

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.

Iskar M, Zeller G, Blattmann P, Campillos M, Kuhn M, Kaminska KH, Runz H, Gavin AC, Pepperkok R, van Noort V, Bork P. Iskar M, et al. Among authors: van noort v. Mol Syst Biol. 2013;9:662. doi: 10.1038/msb.2013.20. Mol Syst Biol. 2013. PMID: 23632384 Free PMC article.

6

Human monogenic disease genes have frequently functionally redundant paralogs.

Chen WH, Zhao XM, van Noort V, Bork P. Chen WH, et al. Among authors: van noort v. PLoS Comput Biol. 2013;9(5):e1003073. doi: 10.1371/journal.pcbi.1003073. Epub 2013 May 16. PLoS Comput Biol. 2013. PMID: 23696728 Free PMC article.

7

Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling.

van Noort V, Schölch S, Iskar M, Zeller G, Ostertag K, Schweitzer C, Werner K, Weitz J, Koch M, Bork P. van Noort V, et al. Cancer Res. 2014 Oct 15;74(20):5690-9. doi: 10.1158/0008-5472.CAN-13-3540. Epub 2014 Jul 18. Cancer Res. 2014. PMID: 25038229 Free article.

8

Comments on "Human dominant disease genes are enriched in paralogs originating from whole genome duplication".

Chen WH, Zhao XM, van Noort V, Bork P. Chen WH, et al. Among authors: van noort v. PLoS Comput Biol. 2014 Jul 31;10(7):e1003758. doi: 10.1371/journal.pcbi.1003758. eCollection 2014 Jul. PLoS Comput Biol. 2014. PMID: 25077479 Free PMC article. No abstract available.

9

CART-a chemical annotation retrieval toolkit.

Deghou S, Zeller G, Iskar M, Driessen M, Castillo M, van Noort V, Bork P. Deghou S, et al. Among authors: van noort v. Bioinformatics. 2016 Sep 15;32(18):2869-71. doi: 10.1093/bioinformatics/btw233. Epub 2016 Jun 2. Bioinformatics. 2016. PMID: 27256313 Free PMC article.

10

Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer.

Iskar M, Bork P, van Noort V. Iskar M, et al. Among authors: van noort v. Mol Cell Oncol. 2015 Feb 11;2(2):e975080. doi: 10.4161/23723556.2014.975080. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308430 Free PMC article.

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