Temperature profoundly affects ataxin-3 fibrillogenesis.
Apicella A, Natalello A, Frana AM, Baserga A, Casari CS, Bottani CE, Doglia SM, Tortora P, Regonesi ME.
Apicella A, et al. Among authors: natalello a.
Biochimie. 2012 Apr;94(4):1026-31. doi: 10.1016/j.biochi.2012.01.002. Epub 2012 Jan 9.
Biochimie. 2012.
PMID: 22234302
Ataxin-3 (AT3) triggers spinocerebellar ataxia type 3 when it carries a polyglutamine stretch expanded beyond a critical threshold. By Fourier transform infrared spectroscopy and atomic force microscopy we previously showed that a normal (AT3Q24) and an expan …
Ataxin-3 (AT3) triggers spinocerebellar ataxia type 3 when it carries a polyglutamine stretch expanded beyond a critical thres …