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IL-21 promotes the pathologic immune response to pneumovirus infection.
Spolski R, Wang L, Wan CK, Bonville CA, Domachowske JB, Kim HP, Yu Z, Leonard WJ. Spolski R, et al. Among authors: yu z. J Immunol. 2012 Feb 15;188(4):1924-32. doi: 10.4049/jimmunol.1100767. Epub 2012 Jan 11. J Immunol. 2012. PMID: 22238461 Free PMC article.
The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses.
Fredriksson K, Mishra A, Lam JK, Mushaben EM, Cuento RA, Meyer KS, Yao X, Keeran KJ, Nugent GZ, Qu X, Yu ZX, Yang Y, Raghavachari N, Dagur PK, McCoy JP, Levine SJ. Fredriksson K, et al. Among authors: yu zx. J Immunol. 2014 May 15;192(10):4497-509. doi: 10.4049/jimmunol.1301234. Epub 2014 Apr 14. J Immunol. 2014. PMID: 24733846 Free PMC article. Clinical Trial.
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.
Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C. Arbore G, et al. Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210. Science. 2016. PMID: 27313051 Free PMC article.
Genetic background-dependent role of Egr1 for eyelid development.
Oh J, Wang Y, Chen S, Li P, Du N, Yu ZX, Butcher D, Gebregiorgis T, Strachan E, Lehmann OJ, Brooks BP, Chan CC, Leonard WJ. Oh J, et al. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7131-E7139. doi: 10.1073/pnas.1705848114. Epub 2017 Aug 4. Proc Natl Acad Sci U S A. 2017. PMID: 28778995 Free PMC article.
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