Xu RH - Search Results

1

Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver.

Xu RH, Rubio D, Roscoe F, Krouse TE, Truckenmiller ME, Norbury CC, Hudson PN, Damon IK, Alcamí A, Sigal LJ. Xu RH, et al. PLoS Pathog. 2012 Jan;8(1):e1002475. doi: 10.1371/journal.ppat.1002475. Epub 2012 Jan 5. PLoS Pathog. 2012. PMID: 22241999 Free PMC article.

2

Memory CD8+ T cells are gatekeepers of the lymph node draining the site of viral infection.

Xu RH, Fang M, Klein-Szanto A, Sigal LJ. Xu RH, et al. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10992-7. doi: 10.1073/pnas.0701822104. Epub 2007 Jun 19. Proc Natl Acad Sci U S A. 2007. PMID: 17578922 Free PMC article.

3

The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination.

Xu RH, Cohen M, Tang Y, Lazear E, Whitbeck JC, Eisenberg RJ, Cohen GH, Sigal LJ. Xu RH, et al. J Exp Med. 2008 Apr 14;205(4):981-92. doi: 10.1084/jem.20071854. Epub 2008 Apr 7. J Exp Med. 2008. PMID: 18391063 Free PMC article.

4

The amino acid sequences flanking an antigenic determinant can strongly affect MHC class I cross-presentation without altering direct presentation.

Ma X, Serna A, Xu RH, Sigal LJ. Ma X, et al. Among authors: xu rh. J Immunol. 2009 Apr 15;182(8):4601-7. doi: 10.4049/jimmunol.0803806. J Immunol. 2009. PMID: 19342634 Free PMC article.

5

Direct presentation is sufficient for an efficient anti-viral CD8+ T cell response.

Xu RH, Remakus S, Ma X, Roscoe F, Sigal LJ. Xu RH, et al. PLoS Pathog. 2010 Feb 12;6(2):e1000768. doi: 10.1371/journal.ppat.1000768. PLoS Pathog. 2010. PMID: 20169189 Free PMC article.

6

Characterization of ectromelia virus deficient in EVM036, the homolog of vaccinia virus F13L, and its application for rapid generation of recombinant viruses.

Roscoe F, Xu RH, Sigal LJ. Roscoe F, et al. Among authors: xu rh. J Virol. 2012 Dec;86(24):13501-7. doi: 10.1128/JVI.01732-12. Epub 2012 Oct 3. J Virol. 2012. PMID: 23035222 Free PMC article.

7

The mature virion of ectromelia virus, a pathogenic poxvirus, is capable of intrahepatic spread and can serve as a target for delayed therapy.

Ma X, Xu RH, Roscoe F, Whitbeck JC, Eisenberg RJ, Cohen GH, Sigal LJ. Ma X, et al. Among authors: xu rh. J Virol. 2013 Jun;87(12):7046-53. doi: 10.1128/JVI.03158-12. Epub 2013 Apr 17. J Virol. 2013. PMID: 23596297 Free PMC article.

8

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection.

Remakus S, Rubio D, Lev A, Ma X, Fang M, Xu RH, Sigal LJ. Remakus S, et al. Among authors: xu rh. Cell Host Microbe. 2013 May 15;13(5):546-557. doi: 10.1016/j.chom.2013.04.004. Cell Host Microbe. 2013. PMID: 23684306 Free PMC article.

9

Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection.

Rubio D, Xu RH, Remakus S, Krouse TE, Truckenmiller ME, Thapa RJ, Balachandran S, Alcamí A, Norbury CC, Sigal LJ. Rubio D, et al. Among authors: xu rh. Cell Host Microbe. 2013 Jun 12;13(6):701-10. doi: 10.1016/j.chom.2013.04.015. Cell Host Microbe. 2013. PMID: 23768494 Free PMC article.

10

MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve Toll-like receptor 2.

Davies ML, Sei JJ, Siciliano NA, Xu RH, Roscoe F, Sigal LJ, Eisenlohr LC, Norbury CC. Davies ML, et al. Among authors: xu rh. J Virol. 2014 Mar;88(6):3557-67. doi: 10.1128/JVI.02776-13. Epub 2014 Jan 8. J Virol. 2014. PMID: 24403581 Free PMC article.

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