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SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.
Tahlan K, Wilson R, Kastrinsky DB, Arora K, Nair V, Fischer E, Barnes SW, Walker JR, Alland D, Barry CE 3rd, Boshoff HI. Tahlan K, et al. Among authors: fischer e. Antimicrob Agents Chemother. 2012 Apr;56(4):1797-809. doi: 10.1128/AAC.05708-11. Epub 2012 Jan 17. Antimicrob Agents Chemother. 2012. PMID: 22252828 Free PMC article.
Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages.
Wehrly TD, Chong A, Virtaneva K, Sturdevant DE, Child R, Edwards JA, Brouwer D, Nair V, Fischer ER, Wicke L, Curda AJ, Kupko JJ 3rd, Martens C, Crane DD, Bosio CM, Porcella SF, Celli J. Wehrly TD, et al. Among authors: fischer er. Cell Microbiol. 2009 Jul;11(7):1128-50. doi: 10.1111/j.1462-5822.2009.01316.x. Epub 2009 Mar 18. Cell Microbiol. 2009. PMID: 19388904 Free PMC article.
Scanning electron microscopy.
Fischer ER, Hansen BT, Nair V, Hoyt FH, Dorward DW. Fischer ER, et al. Curr Protoc Microbiol. 2012 May;Chapter 2:Unit 2B.2.. doi: 10.1002/9780471729259.mc02b02s25. Curr Protoc Microbiol. 2012. PMID: 22549162 Free PMC article.
Scanning Electron Microscopy.
Fischer ER, Hansen BT, Nair V, Hoyt FH, Schwartz CL, Dorward DW. Fischer ER, et al. Curr Protoc. 2024 May;4(5):e1034. doi: 10.1002/cpz1.1034. Curr Protoc. 2024. PMID: 38717581
2,068 results