Goormachtigh G - Search Results

1

Inhibition of latent membrane protein 1 impairs the growth and tumorigenesis of latency II Epstein-Barr virus-transformed T cells.

Ndour PA, Brocqueville G, Ouk TS, Goormachtigh G, Morales O, Mougel A, Bertout J, Melnyk O, Fafeur V, Feuillard J, Coll J, Adriaenssens E. Ndour PA, et al. Among authors: goormachtigh g. J Virol. 2012 Apr;86(7):3934-43. doi: 10.1128/JVI.05747-11. Epub 2012 Jan 18. J Virol. 2012. PMID: 22258264 Free PMC article.

2

Human monocytic cell lines transformed in vitro by Epstein-Barr virus display a type II latency and LMP-1-dependent proliferation.

Masy E, Adriaenssens E, Montpellier C, Crépieux P, Mougel A, Quatannens B, Goormachtigh G, Faumont N, Meggetto F, Auriault C, Groux H, Coll J. Masy E, et al. Among authors: goormachtigh g. J Virol. 2002 Jul;76(13):6460-72. doi: 10.1128/jvi.76.13.6460-6472.2002. J Virol. 2002. PMID: 12050358 Free PMC article.

3

A novel dominant-negative mutant form of Epstein-Barr virus latent membrane protein-1 (LMP1) selectively and differentially impairs LMP1 and TNF signaling pathways.

Adriaenssens E, Mougel A, Goormachtigh G, Loing E, Fafeur V, Auriault C, Coll J. Adriaenssens E, et al. Among authors: goormachtigh g. Oncogene. 2004 Apr 8;23(15):2681-93. doi: 10.1038/sj.onc.1207432. Oncogene. 2004. PMID: 14767477

4

Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways.

Goormachtigh G, Ouk TS, Mougel A, Tranchand-Bunel D, Masy E, Le Clorennec C, Feuillard J, Bornkamm GW, Auriault C, Manet E, Fafeur V, Adriaenssens E, Coll J. Goormachtigh G, et al. J Virol. 2006 Aug;80(15):7382-93. doi: 10.1128/JVI.02052-05. J Virol. 2006. PMID: 16840319 Free PMC article.

5

Anti-apoptotic role of caspase-cleaved GAB1 adaptor protein in hepatocyte growth factor/scatter factor-MET receptor protein signaling.

Le Goff A, Ji Z, Leclercq B, Bourette RP, Mougel A, Guerardel C, de Launoit Y, Vicogne J, Goormachtigh G, Fafeur V. Le Goff A, et al. Among authors: goormachtigh g. J Biol Chem. 2012 Oct 12;287(42):35382-35396. doi: 10.1074/jbc.M112.409797. Epub 2012 Aug 22. J Biol Chem. 2012. PMID: 22915589 Free PMC article.

6

Degradation of the GAB1 adaptor by the ubiquitin-proteasome pathway hampers HGF/SF-MET signaling.

Goormachtigh G, Ji Z, Le Goff A, Fafeur V. Goormachtigh G, et al. Biochem Biophys Res Commun. 2011 Aug 12;411(4):780-5. doi: 10.1016/j.bbrc.2011.07.024. Epub 2011 Jul 18. Biochem Biophys Res Commun. 2011. PMID: 21782801

7

Caspase cleavage of the MET receptor generates an HGF interfering fragment.

Deheuninck J, Foveau B, Goormachtigh G, Leroy C, Ji Z, Tulasne D, Fafeur V. Deheuninck J, et al. Among authors: goormachtigh g. Biochem Biophys Res Commun. 2008 Mar 14;367(3):573-7. doi: 10.1016/j.bbrc.2007.12.177. Epub 2008 Jan 8. Biochem Biophys Res Commun. 2008. PMID: 18187039

8

A one-pot three-segment ligation strategy for protein chemical synthesis.

Ollivier N, Vicogne J, Vallin A, Drobecq H, Desmet R, El Mahdi O, Leclercq B, Goormachtigh G, Fafeur V, Melnyk O. Ollivier N, et al. Among authors: goormachtigh g. Angew Chem Int Ed Engl. 2012 Jan 2;51(1):209-13. doi: 10.1002/anie.201105837. Epub 2011 Nov 16. Angew Chem Int Ed Engl. 2012. PMID: 22095761 No abstract available.

9

Phosphorylation of the MET receptor on juxtamembrane tyrosine residue 1001 inhibits its caspase-dependent cleavage.

Deheuninck J, Goormachtigh G, Foveau B, Ji Z, Leroy C, Ancot F, Villeret V, Tulasne D, Fafeur V. Deheuninck J, et al. Among authors: goormachtigh g. Cell Signal. 2009 Sep;21(9):1455-63. doi: 10.1016/j.cellsig.2009.05.005. Epub 2009 May 18. Cell Signal. 2009. PMID: 19450681

10

Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer.

Duplaquet L, Figeac M, Leprêtre F, Frandemiche C, Villenet C, Sebda S, Sarafan-Vasseur N, Bénozène M, Vinchent A, Goormachtigh G, Wicquart L, Rousseau N, Beaussire L, Truant S, Michel P, Sabourin JC, Galateau-Sallé F, Copin MC, Zalcman G, De Launoit Y, Fafeur V, Tulasne D. Duplaquet L, et al. Among authors: goormachtigh g. Mol Cancer Ther. 2019 Jun;18(6):1137-1148. doi: 10.1158/1535-7163.MCT-18-0582. Epub 2019 Mar 29. Mol Cancer Ther. 2019. PMID: 30926633

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