Medcalf RL - Search Results

1

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.

Niego B, Freeman R, Puschmann TB, Turnley AM, Medcalf RL. Niego B, et al. Among authors: medcalf rl. Blood. 2012 May 17;119(20):4752-61. doi: 10.1182/blood-2011-07-369512. Epub 2012 Jan 19. Blood. 2012. PMID: 22262761 Free article.

2

Plasminogen activator inhibitor type 2: a regulator of monocyte proliferation and differentiation.

Yu H, Maurer F, Medcalf RL. Yu H, et al. Among authors: medcalf rl. Blood. 2002 Apr 15;99(8):2810-8. doi: 10.1182/blood.v99.8.2810. Blood. 2002. PMID: 11929770 Free article.

3

Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury.

Reddrop C, Moldrich RX, Beart PM, Farso M, Liberatore GT, Howells DW, Petersen KU, Schleuning WD, Medcalf RL. Reddrop C, et al. Among authors: medcalf rl. Stroke. 2005 Jun;36(6):1241-6. doi: 10.1161/01.STR.0000166050.84056.48. Epub 2005 May 5. Stroke. 2005. PMID: 15879331

4

Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo.

Weiss TW, Samson AL, Niego B, Daniel PB, Medcalf RL. Weiss TW, et al. Among authors: medcalf rl. FASEB J. 2006 Nov;20(13):2369-71. doi: 10.1096/fj.06-5850fje. Epub 2006 Oct 5. FASEB J. 2006. PMID: 17023520

5

Two conserved regions within the tissue-type plasminogen activator gene promoter mediate regulation by brain-derived neurotrophic factor.

Daniel PB, Lux W, Samson AL, Schleuning WD, Niego B, Weiss TW, Tjärnlund-Wolf A, Medcalf RL. Daniel PB, et al. Among authors: medcalf rl. FEBS J. 2007 May;274(9):2411-23. doi: 10.1111/j.1742-4658.2007.05777.x. Epub 2007 Apr 5. FEBS J. 2007. PMID: 17419735 Free article.

6

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid.

Niego B, Horvath A, Coughlin PB, Pugsley MK, Medcalf RL. Niego B, et al. Among authors: medcalf rl. Blood Coagul Fibrinolysis. 2008 Jun;19(4):322-4. doi: 10.1097/MBC.0b013e3282f54568. Blood Coagul Fibrinolysis. 2008. PMID: 18469556 No abstract available.

7

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function.

Samson AL, Nevin ST, Croucher D, Niego B, Daniel PB, Weiss TW, Moreno E, Monard D, Lawrence DA, Medcalf RL. Samson AL, et al. Among authors: medcalf rl. J Neurochem. 2008 Nov;107(4):1091-101. doi: 10.1111/j.1471-4159.2008.05687.x. Epub 2008 Sep 15. J Neurochem. 2008. PMID: 18796005 Free PMC article.

8

A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury.

Samson AL, Borg RJ, Niego B, Wong CH, Crack PJ, Yongqing T, Medcalf RL. Samson AL, et al. Among authors: medcalf rl. Blood. 2009 Aug 27;114(9):1937-46. doi: 10.1182/blood-2009-02-203448. Epub 2009 Jul 7. Blood. 2009. PMID: 19584397 Free article.

9

Thrombin-induced activation of astrocytes in mixed rat hippocampal cultures is inhibited by soluble thrombomodulin.

Niego B, Samson AL, Petersen KU, Medcalf RL. Niego B, et al. Among authors: medcalf rl. Brain Res. 2011 Mar 24;1381:38-51. doi: 10.1016/j.brainres.2011.01.016. Epub 2011 Jan 15. Brain Res. 2011. PMID: 21241677

10

Plasminogen activation-based thrombolysis for ischaemic stroke: the diversity of targets may demand new approaches.

Medcalf RL. Medcalf RL. Curr Drug Targets. 2011 Nov;12(12):1772-81. doi: 10.2174/138945011797635885. Curr Drug Targets. 2011. PMID: 21707475 Review.

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