Blum G - Search Results

1

Cathepsin B inhibition limits bone metastasis in breast cancer.

Withana NP, Blum G, Sameni M, Slaney C, Anbalagan A, Olive MB, Bidwell BN, Edgington L, Wang L, Moin K, Sloane BF, Anderson RL, Bogyo MS, Parker BS. Withana NP, et al. Among authors: blum g. Cancer Res. 2012 Mar 1;72(5):1199-209. doi: 10.1158/0008-5472.CAN-11-2759. Epub 2012 Jan 19. Cancer Res. 2012. PMID: 22266111 Free PMC article.

2

Functional imaging of legumain in cancer using a new quenched activity-based probe.

Edgington LE, Verdoes M, Ortega A, Withana NP, Lee J, Syed S, Bachmann MH, Blum G, Bogyo M. Edgington LE, et al. Among authors: blum g. J Am Chem Soc. 2013 Jan 9;135(1):174-82. doi: 10.1021/ja307083b. Epub 2012 Dec 18. J Am Chem Soc. 2013. PMID: 23215039 Free PMC article.

3

Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins.

Mullins SR, Sameni M, Blum G, Bogyo M, Sloane BF, Moin K. Mullins SR, et al. Among authors: blum g. Biol Chem. 2012 Dec;393(12):1405-16. doi: 10.1515/hsz-2012-0252. Biol Chem. 2012. PMID: 23667900 Free PMC article.

4

Acid-mediated tumor proteolysis: contribution of cysteine cathepsins.

Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF. Rothberg JM, et al. Among authors: blum g. Neoplasia. 2013 Oct;15(10):1125-37. doi: 10.1593/neo.13946. Neoplasia. 2013. PMID: 24204192 Free PMC article.

5

Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation.

Cavallo-Medved D, Rudy D, Blum G, Bogyo M, Caglic D, Sloane BF. Cavallo-Medved D, et al. Among authors: blum g. Exp Cell Res. 2009 Apr 15;315(7):1234-46. doi: 10.1016/j.yexcr.2009.01.021. Epub 2009 Feb 3. Exp Cell Res. 2009. PMID: 19331819 Free PMC article.

6

VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation.

Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. Chang SH, et al. Among authors: blum g. Cancer Res. 2009 May 15;69(10):4537-44. doi: 10.1158/0008-5472.CAN-08-4539. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435903 Free PMC article.

7

A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages.

Verdoes M, Edgington LE, Scheeren FA, Leyva M, Blum G, Weiskopf K, Bachmann MH, Ellman JA, Bogyo M. Verdoes M, et al. Among authors: blum g. Chem Biol. 2012 May 25;19(5):619-28. doi: 10.1016/j.chembiol.2012.03.012. Chem Biol. 2012. PMID: 22633413 Free PMC article.

8

Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe.

Ren G, Blum G, Verdoes M, Liu H, Syed S, Edgington LE, Gheysens O, Miao Z, Jiang H, Gambhir SS, Bogyo M, Cheng Z. Ren G, et al. Among authors: blum g. PLoS One. 2011;6(11):e28029. doi: 10.1371/journal.pone.0028029. Epub 2011 Nov 21. PLoS One. 2011. PMID: 22132198 Free PMC article.

9

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes.

Edgington LE, Berger AB, Blum G, Albrow VE, Paulick MG, Lineberry N, Bogyo M. Edgington LE, et al. Among authors: blum g. Nat Med. 2009 Aug;15(8):967-73. doi: 10.1038/nm.1938. Epub 2009 Jul 13. Nat Med. 2009. PMID: 19597506 Free PMC article.

10

Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain.

Sexton KB, Witte MD, Blum G, Bogyo M. Sexton KB, et al. Among authors: blum g. Bioorg Med Chem Lett. 2007 Feb 1;17(3):649-53. doi: 10.1016/j.bmcl.2006.10.100. Epub 2006 Nov 6. Bioorg Med Chem Lett. 2007. PMID: 17189693 Free PMC article.

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