Briddon SJ - Search Results

1

Highly potent and selective fluorescent antagonists of the human adenosine A₃ receptor based on the 1,2,4-triazolo[4,3-a]quinoxalin-1-one scaffold.

Vernall AJ, Stoddart LA, Briddon SJ, Hill SJ, Kellam B. Vernall AJ, et al. Among authors: briddon sj. J Med Chem. 2012 Feb 23;55(4):1771-82. doi: 10.1021/jm201722y. Epub 2012 Feb 13. J Med Chem. 2012. PMID: 22277057

2

Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes in agonist potency and relative intrinsic activity.

Cordeaux Y, Briddon SJ, Megson AE, McDonnell J, Dickenson JM, Hill SJ. Cordeaux Y, et al. Among authors: briddon sj. Mol Pharmacol. 2000 Nov;58(5):1075-84. doi: 10.1124/mol.58.5.1075. Mol Pharmacol. 2000. PMID: 11040056

3

Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level.

Briddon SJ, Middleton RJ, Yates AS, George MW, Kellam B, Hill SJ. Briddon SJ, et al. Faraday Discuss. 2004;126:197-207; discussion 245-54. doi: 10.1039/b307407b. Faraday Discuss. 2004. PMID: 14992407

4

Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells.

Briddon SJ, Middleton RJ, Cordeaux Y, Flavin FM, Weinstein JA, George MW, Kellam B, Hill SJ. Briddon SJ, et al. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4673-8. doi: 10.1073/pnas.0400420101. Epub 2004 Mar 16. Proc Natl Acad Sci U S A. 2004. PMID: 15070776 Free PMC article.

5

New fluorescent adenosine A1-receptor agonists that allow quantification of ligand-receptor interactions in microdomains of single living cells.

Middleton RJ, Briddon SJ, Cordeaux Y, Yates AS, Dale CL, George MW, Baker JG, Hill SJ, Kellam B. Middleton RJ, et al. Among authors: briddon sj. J Med Chem. 2007 Feb 22;50(4):782-93. doi: 10.1021/jm061279i. Epub 2007 Jan 24. J Med Chem. 2007. PMID: 17249651

6

Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells.

Cordeaux Y, Briddon SJ, Alexander SP, Kellam B, Hill SJ. Cordeaux Y, et al. Among authors: briddon sj. FASEB J. 2008 Mar;22(3):850-60. doi: 10.1096/fj.07-8180com. Epub 2007 Oct 24. FASEB J. 2008. PMID: 17959910

7

Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand-receptor complexes.

Briddon SJ, Hill SJ. Briddon SJ, et al. Trends Pharmacol Sci. 2007 Dec;28(12):637-45. doi: 10.1016/j.tips.2007.09.008. Epub 2007 Nov 14. Trends Pharmacol Sci. 2007. PMID: 18001848 Free PMC article. Review.

8

Plasma membrane diffusion of G protein-coupled receptor oligomers.

Briddon SJ, Gandía J, Amaral OB, Ferré S, Lluís C, Franco R, Hill SJ, Ciruela F. Briddon SJ, et al. Biochim Biophys Acta. 2008 Dec;1783(12):2262-8. doi: 10.1016/j.bbamcr.2008.07.006. Epub 2008 Jul 21. Biochim Biophys Acta. 2008. PMID: 18691614 Free article.

9

Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions.

May LT, Briddon SJ, Hill SJ. May LT, et al. Among authors: briddon sj. Mol Pharmacol. 2010 Apr;77(4):678-86. doi: 10.1124/mol.109.063065. Epub 2010 Jan 19. Mol Pharmacol. 2010. PMID: 20086038 Free PMC article.

10

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.

Baker JG, Middleton R, Adams L, May LT, Briddon SJ, Kellam B, Hill SJ. Baker JG, et al. Among authors: briddon sj. Br J Pharmacol. 2010 Feb;159(4):772-86. doi: 10.1111/j.1476-5381.2009.00488.x. Epub 2010 Jan 26. Br J Pharmacol. 2010. PMID: 20105183 Free PMC article.

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