Tomlinson IP - Search Results

1

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts.

Leedham SJ, Rodenas-Cuadrado P, Howarth K, Lewis A, Mallappa S, Segditsas S, Davis H, Jeffery R, Rodriguez-Justo M, Keshav S, Travis SP, Graham TA, East J, Clark S, Tomlinson IP. Leedham SJ, et al. Among authors: tomlinson ip. Gut. 2013 Jan;62(1):83-93. doi: 10.1136/gutjnl-2011-301601. Epub 2012 Jan 27. Gut. 2013. PMID: 22287596 Free PMC article.

2

Loss of Bcl-2 expression correlates with tumour recurrence in colorectal cancer.

Ilyas M, Hao XP, Wilkinson K, Tomlinson IP, Abbasi AM, Forbes A, Bodmer WF, Talbot IC. Ilyas M, et al. Among authors: tomlinson ip. Gut. 1998 Sep;43(3):383-7. doi: 10.1136/gut.43.3.383. Gut. 1998. PMID: 9863484 Free PMC article.

3

Molecular characteristics of serrated adenomas of the colorectum.

Sawyer EJ, Cerar A, Hanby AM, Gorman P, Arends M, Talbot IC, Tomlinson IP. Sawyer EJ, et al. Among authors: tomlinson ip. Gut. 2002 Aug;51(2):200-6. doi: 10.1136/gut.51.2.200. Gut. 2002. PMID: 12117880 Free PMC article.

4

Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes.

Crabtree MD, Tomlinson IP, Hodgson SV, Neale K, Phillips RK, Houlston RS. Crabtree MD, et al. Among authors: tomlinson ip. Gut. 2002 Sep;51(3):420-3. doi: 10.1136/gut.51.3.420. Gut. 2002. PMID: 12171967 Free PMC article.

5

Malignant phyllodes tumours show stromal overexpression of c-myc and c-kit.

Sawyer EJ, Poulsom R, Hunt FT, Jeffery R, Elia G, Ellis IO, Ellis P, Tomlinson IP, Hanby AM. Sawyer EJ, et al. Among authors: tomlinson ip. J Pathol. 2003 May;200(1):59-64. doi: 10.1002/path.1318. J Pathol. 2003. PMID: 12692842

6

Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission.

Preston SL, Wong WM, Chan AO, Poulsom R, Jeffery R, Goodlad RA, Mandir N, Elia G, Novelli M, Bodmer WF, Tomlinson IP, Wright NA. Preston SL, et al. Among authors: tomlinson ip. Cancer Res. 2003 Jul 1;63(13):3819-25. Cancer Res. 2003. PMID: 12839979

7

Beta-catenin abnormalities and associated insulin-like growth factor overexpression are important in phyllodes tumours and fibroadenomas of the breast.

Sawyer EJ, Hanby AM, Poulsom R, Jeffery R, Gillett CE, Ellis IO, Ellis P, Tomlinson IP. Sawyer EJ, et al. Among authors: tomlinson ip. J Pathol. 2003 Aug;200(5):627-32. doi: 10.1002/path.1391. J Pathol. 2003. PMID: 12898599

8

Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases.

Crabtree MD, Fletcher C, Churchman M, Hodgson SV, Neale K, Phillips RK, Tomlinson IP. Crabtree MD, et al. Among authors: tomlinson ip. Gut. 2004 Feb;53(2):271-6. doi: 10.1136/gut.2003.015586. Gut. 2004. PMID: 14724163 Free PMC article.

9

Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.

Sieber OM, Howarth KM, Thirlwell C, Rowan A, Mandir N, Goodlad RA, Gilkar A, Spencer-Dene B, Stamp G, Johnson V, Silver A, Yang H, Miller JH, Ilyas M, Tomlinson IP. Sieber OM, et al. Among authors: tomlinson ip. Cancer Res. 2004 Dec 15;64(24):8876-81. doi: 10.1158/0008-5472.CAN-04-2958. Cancer Res. 2004. PMID: 15604247

10

O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions.

Halford S, Rowan A, Sawyer E, Talbot I, Tomlinson I. Halford S, et al. Gut. 2005 Jun;54(6):797-802. doi: 10.1136/gut.2004.059535. Gut. 2005. PMID: 15888787 Free PMC article.

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