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Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing.
García-Herrero CM, Rubio-Cabezas O, Azriel S, Gutierrez-Nogués A, Aragonés A, Vincent O, Campos-Barros A, Argente J, Navas MA. García-Herrero CM, et al. Among authors: gutierrez nogues a. PLoS One. 2012;7(1):e30518. doi: 10.1371/journal.pone.0030518. Epub 2012 Jan 24. PLoS One. 2012. PMID: 22291974 Free PMC article.
Heterogeneity in phenotype of hyperinsulinism caused by activating glucokinase mutations: a novel mutation and its functional characterization.
Martínez R, Gutierrez-Nogués Á, Fernández-Ramos C, Velayos T, Vela A; Spanish Congenital Hyperinsulinism Group; Navas MÁ, Castaño L. Martínez R, et al. Among authors: gutierrez nogues a. Clin Endocrinol (Oxf). 2017 Jun;86(6):778-783. doi: 10.1111/cen.13318. Epub 2017 Mar 27. Clin Endocrinol (Oxf). 2017. PMID: 28247534