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Protein Kinase C Alpha (PKCα) overexpression leads to a better response to retinoid acid therapy through Retinoic Acid Receptor Beta (RARβ) activation in mammary cancer cells.
Bessone MID, Berardi DE, Cirigliano SM, Delbart DI, Peters MG, Todaro LB, Urtreger AJ. Bessone MID, et al. Among authors: berardi de. J Cancer Res Clin Oncol. 2020 Dec;146(12):3241-3253. doi: 10.1007/s00432-020-03368-7. Epub 2020 Aug 31. J Cancer Res Clin Oncol. 2020. PMID: 32865619
All-trans retinoic acid and protein kinase C α/β1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression.
Berardi DE, Ariza Bareño L, Amigo N, Cañonero L, Pelagatti MLN, Motter AN, Taruselli MA, Díaz Bessone MI, Cirigliano SM, Edelstein A, Peters MG, Diament M, Urtreger AJ, Todaro LB. Berardi DE, et al. Sci Rep. 2021 Mar 15;11(1):6044. doi: 10.1038/s41598-021-85344-w. Sci Rep. 2021. PMID: 33723318 Free PMC article.
The synthetic peptide CIGB-300 modulates CK2-dependent signaling pathways affecting the survival and chemoresistance of non-small cell lung cancer cell lines.
Cirigliano SM, Díaz Bessone MI, Berardi DE, Flumian C, Bal de Kier Joffé ED, Perea SE, Farina HG, Todaro LB, Urtreger AJ. Cirigliano SM, et al. Among authors: berardi de. Cancer Cell Int. 2017 Mar 31;17:42. doi: 10.1186/s12935-017-0413-y. eCollection 2017. Cancer Cell Int. 2017. PMID: 28373828 Free PMC article.
19 results