Lu HR - Search Results

1

Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?

Lu HR, Hermans AN, Gallacher DJ. Lu HR, et al. Br J Pharmacol. 2012 Jun;166(4):1490-502. doi: 10.1111/j.1476-5381.2012.01880.x. Br J Pharmacol. 2012. PMID: 22300168 Free PMC article.

2

R 56 865, a Na+/Ca(2+)-overload inhibitor, protects against aconitine-induced cardiac arrhythmias in vivo.

Lu HR, De Clerck F. Lu HR, et al. J Cardiovasc Pharmacol. 1993 Jul;22(1):120-5. doi: 10.1097/00005344-199307000-00019. J Cardiovasc Pharmacol. 1993. PMID: 7690083

3

Antiarrhythmic effects of nebivolol in experimental models in vivo.

Lu HR, Remeysen P, De Clerck F. Lu HR, et al. J Cardiovasc Pharmacol. 1994 Dec;24(6):986-93. doi: 10.1097/00005344-199424060-00018. J Cardiovasc Pharmacol. 1994. PMID: 7898084

4

Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.

Lu HR, Yang P, Remeysen P, Saels A, Dai DZ, De Clerck F. Lu HR, et al. Eur J Pharmacol. 1999 Jan 22;365(2-3):233-9. doi: 10.1016/s0014-2999(98)00878-4. Eur J Pharmacol. 1999. PMID: 9988107

5

Reduction in QT dispersion and ventricular arrhythmias by ischaemic preconditioning in anaesthetized, normotensive and spontaneously hypertensive rats.

Lu HR, Yu F, Dai DZ, Remeysen P, De Clerck F. Lu HR, et al. Fundam Clin Pharmacol. 1999;13(4):445-54. doi: 10.1111/j.1472-8206.1999.tb00002.x. Fundam Clin Pharmacol. 1999. PMID: 10456285

6

Are there sex-specific differences in ventricular repolarization or in drug-induced early afterdepolarizations in isolated rabbit purkinje fibers?

Lu HR, Mariën R, Saels A, De Clerck F. Lu HR, et al. J Cardiovasc Pharmacol. 2000 Jul;36(1):132-9. doi: 10.1097/00005344-200007000-00018. J Cardiovasc Pharmacol. 2000. PMID: 10892671

7

Nonselective I(Kr)-blockers do not induce torsades de pointes in the anesthetized rabbit during alpha1-adrenoceptor stimulation.

Lu HR, Remeysen P, De Clerck F. Lu HR, et al. J Cardiovasc Pharmacol. 2000 Dec;36(6):728-36. doi: 10.1097/00005344-200012000-00007. J Cardiovasc Pharmacol. 2000. PMID: 11117372

8

Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers.

Lu HR, Mariën R, Saels A, De Clerck F. Lu HR, et al. J Cardiovasc Electrophysiol. 2001 Jan;12(1):93-102. doi: 10.1046/j.1540-8167.2001.00093.x. J Cardiovasc Electrophysiol. 2001. PMID: 11204092

9

Female gender is a risk factor for drug-induced long QT and cardiac arrhythmias in an in vivo rabbit model.

Lu HR, Remeysen P, Somers K, Saels A, De Clerck F. Lu HR, et al. J Cardiovasc Electrophysiol. 2001 May;12(5):538-45. doi: 10.1046/j.1540-8167.2001.00538.x. J Cardiovasc Electrophysiol. 2001. PMID: 11386514

10

In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: application to the preclinical cardiovascular safety pharmacology of a new chemical entity.

De Clerck F, Van de Water A, D'Aubioul J, Lu HR, van Rossem K, Hermans A, Van Ammel K. De Clerck F, et al. Among authors: lu hr. Fundam Clin Pharmacol. 2002 Apr;16(2):125-40. doi: 10.1046/j.1472-8206.2002.00081.x. Fundam Clin Pharmacol. 2002. PMID: 12031065 Review.

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