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Common variants at 11p13 are associated with susceptibility to tuberculosis.
Thye T, Owusu-Dabo E, Vannberg FO, van Crevel R, Curtis J, Sahiratmadja E, Balabanova Y, Ehmen C, Muntau B, Ruge G, Sievertsen J, Gyapong J, Nikolayevskyy V, Hill PC, Sirugo G, Drobniewski F, van de Vosse E, Newport M, Alisjahbana B, Nejentsev S, Ottenhoff TH, Hill AV, Horstmann RD, Meyer CG. Thye T, et al. Among authors: horstmann rd. Nat Genet. 2012 Feb 5;44(3):257-9. doi: 10.1038/ng.1080. Nat Genet. 2012. PMID: 22306650 Free PMC article.
ALOX5 variants associated with susceptibility to human pulmonary tuberculosis.
Herb F, Thye T, Niemann S, Browne EN, Chinbuah MA, Gyapong J, Osei I, Owusu-Dabo E, Werz O, Rüsch-Gerdes S, Horstmann RD, Meyer CG. Herb F, et al. Among authors: horstmann rd. Hum Mol Genet. 2008 Apr 1;17(7):1052-60. doi: 10.1093/hmg/ddm378. Epub 2008 Jan 3. Hum Mol Genet. 2008. PMID: 18174194
Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.
Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium; Morris AP, Meyer CG, Horstmann RD, Hill AVS. Thye T, et al. Among authors: horstmann rd. Nat Genet. 2010 Sep;42(9):739-741. doi: 10.1038/ng.639. Epub 2010 Aug 8. Nat Genet. 2010. PMID: 20694014 Free PMC article.
Genome-wide association study indicates two novel resistance loci for severe malaria.
Timmann C, Thye T, Vens M, Evans J, May J, Ehmen C, Sievertsen J, Muntau B, Ruge G, Loag W, Ansong D, Antwi S, Asafo-Adjei E, Nguah SB, Kwakye KO, Akoto AO, Sylverken J, Brendel M, Schuldt K, Loley C, Franke A, Meyer CG, Agbenyega T, Ziegler A, Horstmann RD. Timmann C, et al. Among authors: horstmann rd. Nature. 2012 Sep 20;489(7416):443-6. doi: 10.1038/nature11334. Epub 2012 Aug 15. Nature. 2012. PMID: 22895189
Evolution and transmission of drug-resistant tuberculosis in a Russian population.
Casali N, Nikolayevskyy V, Balabanova Y, Harris SR, Ignatyeva O, Kontsevaya I, Corander J, Bryant J, Parkhill J, Nejentsev S, Horstmann RD, Brown T, Drobniewski F. Casali N, et al. Among authors: horstmann rd. Nat Genet. 2014 Mar;46(3):279-86. doi: 10.1038/ng.2878. Epub 2014 Jan 26. Nat Genet. 2014. PMID: 24464101 Free PMC article.
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Curtis J, Luo Y, Zenner HL, Cuchet-Lourenço D, Wu C, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, Thye T, Meyer CG, Nürnberg P, Horstmann RD, Drobniewski F, Plagnol V, Barrett JC, Nejentsev S. Curtis J, et al. Among authors: horstmann rd. Nat Genet. 2015 May;47(5):523-527. doi: 10.1038/ng.3248. Epub 2015 Mar 16. Nat Genet. 2015. PMID: 25774636 Free PMC article.
147 results