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Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.
Descamps D, Le Gars M, Balloy V, Barbier D, Maschalidi S, Tohme M, Chignard M, Ramphal R, Manoury B, Sallenave JM. Descamps D, et al. Among authors: le gars m. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1619-24. doi: 10.1073/pnas.1108464109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307620 Free PMC article.
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.
Le Gars M, Descamps D, Roussel D, Saussereau E, Guillot L, Ruffin M, Tabary O, Hong SS, Boulanger P, Paulais M, Malleret L, Belaaouaj A, Edelman A, Huerre M, Chignard M, Sallenave JM. Le Gars M, et al. Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6. Am J Respir Crit Care Med. 2013. PMID: 23220915
[iNKT cells: potential therapeutic targets to fight anthrax].
Le Gars M, Haustant M, Klezovich-Benard M, Paget C, Trottein F, Goossens PL, Tournier JN. Le Gars M, et al. Med Sci (Paris). 2017 May;33(5):488-490. doi: 10.1051/medsci/20173305010. Epub 2017 Jun 14. Med Sci (Paris). 2017. PMID: 28612722 Free article. French. No abstract available.
Pregnancy-Induced Alterations in NK Cell Phenotype and Function.
Le Gars M, Seiler C, Kay AW, Bayless NL, Starosvetsky E, Moore L, Shen-Orr SS, Aziz N, Khatri P, Dekker CL, Swan GE, Davis MM, Holmes S, Blish CA. Le Gars M, et al. Front Immunol. 2019 Oct 23;10:2469. doi: 10.3389/fimmu.2019.02469. eCollection 2019. Front Immunol. 2019. PMID: 31708922 Free PMC article.
Safety and Humoral Immunogenicity of Different Dose Levels of Ad26.COV2.S as a 2-Dose Regimen in COVID-19 Vaccine-Naïve Healthy Adults: A Phase 3 Randomized Clinical Trial.
Rezelj VV, Paddenburg F, Diegbe ME, Nangosyah J, Reisinger EC, Hu W, Truyers C, Scheper G, Le Gars M, Hendriks J, Struyf F, Douoguih M, Schuitemaker H, Ruiz-Guiñazú J. Rezelj VV, et al. Among authors: le gars m. Vaccines (Basel). 2024 Oct 3;12(10):1136. doi: 10.3390/vaccines12101136. Vaccines (Basel). 2024. PMID: 39460303 Free PMC article.
Ad26.COV2.S COVID-19 Vaccine Safety And Immunogenicity in Adolescents 16-17 Years of Age.
Ruiz-Guiñazú J, Le Gars M, Cárdenas V, Vaissière N, Sadoff J, Truyers C, Hendriks J, Scheper G, de Groot AM, Struyf F, Schuitemaker H, Douoguih M. Ruiz-Guiñazú J, et al. Among authors: le gars m. J Pediatric Infect Dis Soc. 2024 Nov 27;13(11):599-601. doi: 10.1093/jpids/piae098. J Pediatric Infect Dis Soc. 2024. PMID: 39340467 Free PMC article.
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