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Type 1 interferons cool the inflamed brain.
Axtell RC, Steinman L. Axtell RC, et al. Immunity. 2008 May;28(5):600-2. doi: 10.1016/j.immuni.2008.04.006. Immunity. 2008. PMID: 18482563 Free article.
Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice.
Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, Raine CS, Sobel RA, Han DK, Weissman I, Steinman L. Han MH, et al. Among authors: axtell rc. J Exp Med. 2012 Jul 2;209(7):1325-34. doi: 10.1084/jem.20101974. Epub 2012 Jun 25. J Exp Med. 2012. PMID: 22734047 Free PMC article.
Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.
Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, Andreasson K, Herzenberg LA, Herzenberg LA, Steinman L. Grant JL, et al. Among authors: axtell rc. Sci Transl Med. 2012 Aug 1;4(145):145ra105. doi: 10.1126/scitranslmed.3004145. Sci Transl Med. 2012. PMID: 22855462 Free PMC article.
Inhibitory role for GABA in autoimmune inflammation.
Bhat R, Axtell R, Mitra A, Miranda M, Lock C, Tsien RW, Steinman L. Bhat R, et al. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2580-5. doi: 10.1073/pnas.0915139107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133656 Free PMC article.
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis.
Axtell RC, de Jong BA, Boniface K, van der Voort LF, Bhat R, De Sarno P, Naves R, Han M, Zhong F, Castellanos JG, Mair R, Christakos A, Kolkowitz I, Katz L, Killestein J, Polman CH, de Waal Malefyt R, Steinman L, Raman C. Axtell RC, et al. Nat Med. 2010 Apr;16(4):406-12. doi: 10.1038/nm.2110. Epub 2010 Mar 28. Nat Med. 2010. PMID: 20348925 Free PMC article.
135 results