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Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, Serhan CN, Heinecke JW, Coleman RA, Bornfeldt KE. Kanter JE, et al. Among authors: heinecke jw. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):E715-24. doi: 10.1073/pnas.1111600109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22308341 Free PMC article.
S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation.
Averill MM, Barnhart S, Becker L, Li X, Heinecke JW, Leboeuf RC, Hamerman JA, Sorg C, Kerkhoff C, Bornfeldt KE. Averill MM, et al. Among authors: heinecke jw. Circulation. 2011 Mar 22;123(11):1216-26. doi: 10.1161/CIRCULATIONAHA.110.985523. Epub 2011 Mar 7. Circulation. 2011. PMID: 21382888 Free PMC article.
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Bergt C, Pennathur S, Fu X, Byun J, O'Brien K, McDonald TO, Singh P, Anantharamaiah GM, Chait A, Brunzell J, Geary RL, Oram JF, Heinecke JW. Bergt C, et al. Among authors: heinecke jw. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13032-7. doi: 10.1073/pnas.0405292101. Epub 2004 Aug 23. Proc Natl Acad Sci U S A. 2004. PMID: 15326314 Free PMC article.
Unique proteomic signatures distinguish macrophages and dendritic cells.
Becker L, Liu NC, Averill MM, Yuan W, Pamir N, Peng Y, Irwin AD, Fu X, Bornfeldt KE, Heinecke JW. Becker L, et al. Among authors: heinecke jw. PLoS One. 2012;7(3):e33297. doi: 10.1371/journal.pone.0033297. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22428014 Free PMC article.
Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.
Kanter JE, Shao B, Kramer F, Barnhart S, Shimizu-Albergine M, Vaisar T, Graham MJ, Crooke RM, Manuel CR, Haeusler RA, Mar D, Bomsztyk K, Hokanson JE, Kinney GL, Snell-Bergeon JK, Heinecke JW, Bornfeldt KE. Kanter JE, et al. Among authors: heinecke jw. J Clin Invest. 2019 Jul 11;129(10):4165-4179. doi: 10.1172/JCI127308. J Clin Invest. 2019. PMID: 31295146 Free PMC article.
CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins.
Shimizu-Albergine M, Basu D, Kanter JE, Kramer F, Kothari V, Barnhart S, Thornock C, Mullick AE, Clouet-Foraison N, Vaisar T, Heinecke JW, Hegele RA, Goldberg IJ, Bornfeldt KE. Shimizu-Albergine M, et al. Among authors: heinecke jw. J Clin Invest. 2021 Nov 15;131(22):e153285. doi: 10.1172/JCI153285. J Clin Invest. 2021. PMID: 34491909 Free PMC article.
272 results