Sarver JG - Search Results

1

Syntheses of 2,3-diarylated 2H-benzo[e][1,2]thiazine 1,1-dioxides and their 3,4-dihydro derivatives, and assessment of their inhibitory activity against MCF-7 breast cancer cells.

Shan YY, Zhang CM, Tang LQ, Liu ZP, Bearss NR, Sarver JG, Luniwal A, Erhardt PW. Shan YY, et al. Among authors: sarver jg. Med Chem. 2011 Nov;7(6):561-71. doi: 10.2174/157340611797928307. Med Chem. 2011. PMID: 22313296

2

Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I.

Khupse RS, Sarver JG, Trendel JA, Bearss NR, Reese MD, Wiese TE, Boue SM, Burow ME, Cleveland TE, Bhatnagar D, Erhardt PW. Khupse RS, et al. Among authors: sarver jg. J Med Chem. 2011 May 26;54(10):3506-23. doi: 10.1021/jm101619e. Epub 2011 Apr 22. J Med Chem. 2011. PMID: 21513275

3

6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability.

Du S, Sarver JG, Trabbic CJ, Erhardt PW, Schroering A, Maltese WA. Du S, et al. Among authors: sarver jg. Cancer Chemother Pharmacol. 2019 Feb;83(2):237-254. doi: 10.1007/s00280-018-3726-1. Epub 2018 Nov 13. Cancer Chemother Pharmacol. 2019. PMID: 30426158 Free PMC article.

4

Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis.

Kress BJ, Kim DH, Mayo JR, Farris JT, Heck B, Sarver JG, Andy D, Trendel JA, Heck BE, Erhardt PW. Kress BJ, et al. Among authors: sarver jg. J Med Chem. 2021 May 27;64(10):6996-7032. doi: 10.1021/acs.jmedchem.1c00560. Epub 2021 May 14. J Med Chem. 2021. PMID: 33988379

5

The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma.

Li Z, Mbah NE, Overmeyer JH, Sarver JG, George S, Trabbic CJ, Erhardt PW, Maltese WA. Li Z, et al. Among authors: sarver jg. BMC Cancer. 2019 Jan 16;19(1):77. doi: 10.1186/s12885-019-5288-y. BMC Cancer. 2019. PMID: 30651087 Free PMC article.

6

Microplate screening of the differential effects of test agents on Hoechst 33342, rhodamine 123, and rhodamine 6G accumulation in breast cancer cells that overexpress P-glycoprotein.

Sarver JG, Klis WA, Byers JP, Erhardt PW. Sarver JG, et al. J Biomol Screen. 2002 Feb;7(1):29-34. doi: 10.1177/108705710200700105. J Biomol Screen. 2002. PMID: 11897053

7

Early stage efficacy and toxicology screening for antibiotics and enzyme inhibitors.

Sarver JG, Trendel JA, Bearss NR, Wang L, Luniwal A, Erhardt PW, Viola RE. Sarver JG, et al. J Biomol Screen. 2012 Jun;17(5):673-82. doi: 10.1177/1087057112438769. Epub 2012 Mar 29. J Biomol Screen. 2012. PMID: 22460173

8

Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α.

Gordon DM, Neifer KL, Hamoud AA, Hawk CF, Nestor-Kalinoski AL, Miruzzi SA, Morran MP, Adeosun SO, Sarver JG, Erhardt PW, McCullumsmith RE, Stec DE, Hinds TD Jr. Gordon DM, et al. Among authors: sarver jg. J Biol Chem. 2020 Jul 17;295(29):9804-9822. doi: 10.1074/jbc.RA120.013700. Epub 2020 May 13. J Biol Chem. 2020. PMID: 32404366 Free PMC article.

9

Investigating the Potential to Deliver and Maintain Plasma and Brain Levels of a Novel Practically Insoluble Methuosis Inducing Anticancer Agent 5-Methoxy MOMIPP Through an Injectable In Situ Forming Thermoresponsive Hydrogel Formulation.

Oppong F, Li Z, Fakhrabadi EA, Raorane T, Giri PM, Liberatore MW, Sarver JG, Trabbic CJ, Hosier CE, Erhardt PW, Maltese WA, Nesamony J. Oppong F, et al. Among authors: sarver jg. J Pharm Sci. 2020 Sep;109(9):2719-2728. doi: 10.1016/j.xphs.2020.05.014. Epub 2020 May 28. J Pharm Sci. 2020. PMID: 32473210

10

Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells.

Heyza JR, Arora S, Zhang H, Conner KL, Lei W, Floyd AM, Deshmukh RR, Sarver J, Trabbic CJ, Erhardt P, Chan TH, Dou QP, Patrick SM. Heyza JR, et al. Nutrients. 2018 Nov 3;10(11):1644. doi: 10.3390/nu10111644. Nutrients. 2018. PMID: 30400270 Free PMC article.

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