Scammells PJ - Search Results

1

Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptor.

Valant C, Aurelio L, Devine SM, Ashton TD, White JM, Sexton PM, Christopoulos A, Scammells PJ. Valant C, et al. Among authors: scammells pj. J Med Chem. 2012 Mar 8;55(5):2367-75. doi: 10.1021/jm201600e. Epub 2012 Feb 17. J Med Chem. 2012. PMID: 22315963

2

Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogues of 1-methylisoguanosine.

Harden FA, Quinn RJ, Scammells PJ. Harden FA, et al. Among authors: scammells pj. J Med Chem. 1991 Sep;34(9):2892-8. doi: 10.1021/jm00113a031. J Med Chem. 1991. PMID: 1895306

3

XH-14 analogues as adenosine antagonists.

Scammells PJ, Baker SP, Beauglehole AR. Scammells PJ, et al. Bioorg Med Chem. 1998 Sep;6(9):1517-24. doi: 10.1016/s0968-0896(98)00093-5. Bioorg Med Chem. 1998. PMID: 9801823

4

N6-(5,6-epoxynorbornyl)adenosine analogs as A1 adenosine agonists.

Wright DM, Baker SP, Stewart SG, Scammells PJ. Wright DM, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3647-8. doi: 10.1016/s0960-894x(98)00668-4. Bioorg Med Chem Lett. 1998. PMID: 9934487

5

Adenosine receptor ligands with oxygenated N6-substituents.

Hutchinson SA, Baker SP, Scammells PJ. Hutchinson SA, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 1999 Apr 5;9(7):933-6. doi: 10.1016/s0960-894x(99)00109-2. Bioorg Med Chem Lett. 1999. PMID: 10230614

6

Fluorosulfonyl-substituted xanthines as selective irreversible antagonists for the A(1)-adenosine receptor.

Beauglehole AR, Baker SP, Scammells PJ. Beauglehole AR, et al. Among authors: scammells pj. J Med Chem. 2000 Dec 28;43(26):4973-80. doi: 10.1021/jm000181f. J Med Chem. 2000. PMID: 11150167

7

2-Amino-3-aroyl-4,5-alkylthiophenes: agonist allosteric enhancers at human A(1) adenosine receptors.

Tranberg CE, Zickgraf A, Giunta BN, Luetjens H, Figler H, Murphree LJ, Falke R, Fleischer H, Linden J, Scammells PJ, Olsson RA. Tranberg CE, et al. Among authors: scammells pj. J Med Chem. 2002 Jan 17;45(2):382-9. doi: 10.1021/jm010081p. J Med Chem. 2002. PMID: 11784142

8

New 2,N6-disubstituted adenosines: potent and selective A1 adenosine receptor agonists.

Hutchinson SA, Baker SP, Scammells PJ. Hutchinson SA, et al. Among authors: scammells pj. Bioorg Med Chem. 2002 Apr;10(4):1115-22. doi: 10.1016/s0968-0896(01)00384-4. Bioorg Med Chem. 2002. PMID: 11836122

9

New irreversible adenosine A(1) antagonists based on FSCPX.

Beauglehole AR, Baker SP, Scammells PJ. Beauglehole AR, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3179-82. doi: 10.1016/s0960-894x(02)00639-x. Bioorg Med Chem Lett. 2002. PMID: 12372528

10

2-Amino-3-benzoylthiophene allosteric enhancers of A1 adenosine agonist binding: new 3, 4-, and 5-modifications.

Lütjens H, Zickgraf A, Figler H, Linden J, Olsson RA, Scammells PJ. Lütjens H, et al. Among authors: scammells pj. J Med Chem. 2003 May 8;46(10):1870-7. doi: 10.1021/jm020295m. J Med Chem. 2003. PMID: 12723950

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