Blood clotting factor IX Niigata: substitution of alanine-390 by valine in the catalytic domain.
Sugimoto M, Miyata T, Kawabata S, Yoshioka A, Fukui H, Takahashi H, Iwanaga S.
Sugimoto M, et al. Among authors: yoshioka a.
J Biochem. 1988 Dec;104(6):878-80. doi: 10.1093/oxfordjournals.jbchem.a122575.
J Biochem. 1988.
PMID: 3243764
Free article.
Factor IX Niigata is a mutant factor IX responsible for the moderately severe hemophilia B in a patient who has a normal level of factor IX antigen with reduced clotting activity (1-4% of normal). We reported previously that the purified mutant protein could …
Factor IX Niigata is a mutant factor IX responsible for the moderately severe hemophilia B in a patient who has a norma …