Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.
Hunter JE, Campbell AE, Butterworth JA, Sellier H, Hannaway NL, Luli S, Floudas A, Kenneth NS, Moore AJ, Brownridge PJ, Thomas HD, Coxhead J, Taylor L, Leary P, Hasoon MSR, Knight AM, Garrett MD, Collins I, Eyers CE, Perkins ND.
Hunter JE, et al. Among authors: kenneth ns.
Biochem J. 2022 Oct 14;479(19):2087-2113. doi: 10.1042/BCJ20220089.
Biochem J. 2022.
PMID: 36240065
Free PMC article.
No abstract available.