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814 results

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Page 1
A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
Seeherman HJ, Berasi SP, Brown CT, Martinez RX, Juo ZS, Jelinsky S, Cain MJ, Grode J, Tumelty KE, Bohner M, Grinberg O, Orr N, Shoseyov O, Eyckmans J, Chen C, Morales PR, Wilson CG, Vanderploeg EJ, Wozney JM. Seeherman HJ, et al. Among authors: cain mj. Sci Transl Med. 2019 Apr 24;11(489):eaar4953. doi: 10.1126/scitranslmed.aar4953. Sci Transl Med. 2019. PMID: 31019025
Hit to lead studies on (hetero)arylpyrimidines--agonists of the canonical Wnt-beta-catenin cellular messaging system.
Gilbert AM, Bursavich MG, Alon N, Bhat BM, Bex FJ, Cain M, Coleburn V, Gironda V, Green P, Hauze DB, Kharode Y, Krishnamurthy G, Kirisits M, Lam HS, Liu YB, Lombardi S, Matteo J, Murrills R, Robinson JA, Selim S, Sharp M, Unwalla R, Varadarajan U, Zhao W, Yaworsky PJ. Gilbert AM, et al. Among authors: cain m. Bioorg Med Chem Lett. 2010 Jan 1;20(1):366-70. doi: 10.1016/j.bmcl.2009.10.093. Epub 2009 Oct 25. Bioorg Med Chem Lett. 2010. PMID: 19897365
Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model.
Bhatta A, Sangani R, Kolhe R, Toque HA, Cain M, Wong A, Howie N, Shinde R, Elsalanty M, Yao L, Chutkan N, Hunter M, Caldwell RB, Isales C, Caldwell RW, Fulzele S. Bhatta A, et al. Among authors: cain m. Mol Cell Endocrinol. 2016 Feb 15;422:211-220. doi: 10.1016/j.mce.2015.12.005. Epub 2015 Dec 17. Mol Cell Endocrinol. 2016. PMID: 26704078 Free PMC article.
Amino acids as signaling molecules modulating bone turnover.
Ding KH, Cain M, Davis M, Bergson C, McGee-Lawrence M, Perkins C, Hardigan T, Shi X, Zhong Q, Xu J, Bollag WB, Hill W, Elsalanty M, Hunter M, Isales MC, Lopez P, Hamrick M, Isales CM. Ding KH, et al. Among authors: cain m. Bone. 2018 Oct;115:15-24. doi: 10.1016/j.bone.2018.02.028. Epub 2018 Feb 27. Bone. 2018. PMID: 29499416 Free PMC article. Review.
Characterization of binding mode of action of a blocking anti-platelet-derived growth factor (PDGF)-B monoclonal antibody, MOR8457, reveals conformational flexibility and avidity needed for PDGF-BB to bind PDGF receptor-β.
Kuai J, Mosyak L, Brooks J, Cain M, Carven GJ, Ogawa S, Ishino T, Tam M, Lavallie ER, Yang Z, Ponsel D, Rauchenberger R, Arch R, Pullen N. Kuai J, et al. Among authors: cain m. Biochemistry. 2015 Mar 17;54(10):1918-29. doi: 10.1021/bi5015425. Epub 2015 Mar 6. Biochemistry. 2015. PMID: 25707433
Adherence to follow-up ten years after hypospadias repair.
Batra NV, Heiman J, Koehlinger J, Dangle P, Meldrum KK, Whittam BM, Szymanski KM, Rink RC, Kaefer M, Cain MP, Misseri R, Roth JD. Batra NV, et al. Among authors: cain mp. J Pediatr Urol. 2025 Jan 6:S1477-5131(24)00690-9. doi: 10.1016/j.jpurol.2024.12.026. Online ahead of print. J Pediatr Urol. 2025. PMID: 39824717 No abstract available.
814 results