Fraser JA - Search Results

1

Microevolution of Cryptococcus neoformans driven by massive tandem gene amplification.

Chow EW, Morrow CA, Djordjevic JT, Wood IA, Fraser JA. Chow EW, et al. Among authors: fraser ja. Mol Biol Evol. 2012 Aug;29(8):1987-2000. doi: 10.1093/molbev/mss066. Epub 2012 Feb 14. Mol Biol Evol. 2012. PMID: 22334577

2

Chromosomal translocation and segmental duplication in Cryptococcus neoformans.

Fraser JA, Huang JC, Pukkila-Worley R, Alspaugh JA, Mitchell TG, Heitman J. Fraser JA, et al. Eukaryot Cell. 2005 Feb;4(2):401-6. doi: 10.1128/EC.4.2.401-406.2005. Eukaryot Cell. 2005. PMID: 15701802 Free PMC article.

3

Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment.

Kavanaugh LA, Fraser JA, Dietrich FS. Kavanaugh LA, et al. Among authors: fraser ja. Mol Biol Evol. 2006 Oct;23(10):1879-90. doi: 10.1093/molbev/msl070. Epub 2006 Jul 26. Mol Biol Evol. 2006. PMID: 16870684

4

Sexual reproduction and dimorphism in the pathogenic basidiomycetes.

Morrow CA, Fraser JA. Morrow CA, et al. Among authors: fraser ja. FEMS Yeast Res. 2009 Mar;9(2):161-77. doi: 10.1111/j.1567-1364.2008.00475.x. FEMS Yeast Res. 2009. PMID: 19220864 Review.

5

Crystallization and preliminary X-ray analysis of mycophenolic acid-resistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus.

Morrow CA, Stamp A, Valkov E, Kobe B, Fraser JA. Morrow CA, et al. Among authors: fraser ja. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1104-7. doi: 10.1107/S1744309110031659. Epub 2010 Aug 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823538 Free PMC article.

6

Nitrogen metabolite repression of metabolism and virulence in the human fungal pathogen Cryptococcus neoformans.

Lee IR, Chow EW, Morrow CA, Djordjevic JT, Fraser JA. Lee IR, et al. Among authors: fraser ja. Genetics. 2011 Jun;188(2):309-23. doi: 10.1534/genetics.111.128538. Epub 2011 Mar 24. Genetics. 2011. PMID: 21441208 Free PMC article.

7

A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence.

Morrow CA, Lee IR, Chow EW, Ormerod KL, Goldinger A, Byrnes EJ 3rd, Nielsen K, Heitman J, Schirra HJ, Fraser JA. Morrow CA, et al. Among authors: fraser ja. mBio. 2012 Feb 28;3(2):e00310-11. doi: 10.1128/mBio.00310-11. Print 2012. mBio. 2012. PMID: 22375073 Free PMC article.

8

Characterization of an Nmr homolog that modulates GATA factor-mediated nitrogen metabolite repression in Cryptococcus neoformans.

Lee IR, Lim JW, Ormerod KL, Morrow CA, Fraser JA. Lee IR, et al. Among authors: fraser ja. PLoS One. 2012;7(3):e32585. doi: 10.1371/journal.pone.0032585. Epub 2012 Mar 28. PLoS One. 2012. PMID: 22470421 Free PMC article.

9

De novo GTP biosynthesis is critical for virulence of the fungal pathogen Cryptococcus neoformans.

Morrow CA, Valkov E, Stamp A, Chow EW, Lee IR, Wronski A, Williams SJ, Hill JM, Djordjevic JT, Kappler U, Kobe B, Fraser JA. Morrow CA, et al. Among authors: fraser ja. PLoS Pathog. 2012;8(10):e1002957. doi: 10.1371/journal.ppat.1002957. Epub 2012 Oct 11. PLoS Pathog. 2012. PMID: 23071437 Free PMC article.

10

Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase.

Lee YT, Cui CJ, Chow EW, Pue N, Lonhienne T, Wang JG, Fraser JA, Guddat LW. Lee YT, et al. Among authors: fraser ja. J Med Chem. 2013 Jan 10;56(1):210-9. doi: 10.1021/jm301501k. Epub 2012 Dec 31. J Med Chem. 2013. PMID: 23237384

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