Holyoake TL - Search Results

1

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib.

Li L, Wang L, Li L, Wang Z, Ho Y, McDonald T, Holyoake TL, Chen W, Bhatia R. Li L, et al. Among authors: holyoake tl. Cancer Cell. 2012 Feb 14;21(2):266-81. doi: 10.1016/j.ccr.2011.12.020. Cancer Cell. 2012. PMID: 22340598 Free PMC article.

2

Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.

Zhang B, Strauss AC, Chu S, Li M, Ho Y, Shiang KD, Snyder DS, Huettner CS, Shultz L, Holyoake T, Bhatia R. Zhang B, et al. Cancer Cell. 2010 May 18;17(5):427-42. doi: 10.1016/j.ccr.2010.03.011. Cancer Cell. 2010. PMID: 20478526 Free PMC article.

3

Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606.

Konig H, Holyoake TL, Bhatia R. Konig H, et al. Among authors: holyoake tl. Blood. 2008 Feb 15;111(4):2329-38. doi: 10.1182/blood-2007-05-092056. Epub 2007 Dec 4. Blood. 2008. PMID: 18056843 Free PMC article.

4

Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells.

Konig H, Copland M, Chu S, Jove R, Holyoake TL, Bhatia R. Konig H, et al. Among authors: holyoake tl. Cancer Res. 2008 Dec 1;68(23):9624-33. doi: 10.1158/0008-5472.CAN-08-1131. Cancer Res. 2008. PMID: 19047139 Free PMC article.

5

Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia.

Zhang B, Ho YW, Huang Q, Maeda T, Lin A, Lee SU, Hair A, Holyoake TL, Huettner C, Bhatia R. Zhang B, et al. Among authors: holyoake tl. Cancer Cell. 2012 Apr 17;21(4):577-92. doi: 10.1016/j.ccr.2012.02.018. Cancer Cell. 2012. PMID: 22516264 Free PMC article.

6

Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-β-catenin signaling.

Zhang B, Li M, McDonald T, Holyoake TL, Moon RT, Campana D, Shultz L, Bhatia R. Zhang B, et al. Among authors: holyoake tl. Blood. 2013 Mar 7;121(10):1824-38. doi: 10.1182/blood-2012-02-412890. Epub 2013 Jan 8. Blood. 2013. PMID: 23299311 Free PMC article.

7

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.

Gallipoli P, Cook A, Rhodes S, Hopcroft L, Wheadon H, Whetton AD, Jørgensen HG, Bhatia R, Holyoake TL. Gallipoli P, et al. Among authors: holyoake tl. Blood. 2014 Aug 28;124(9):1492-501. doi: 10.1182/blood-2013-12-545640. Epub 2014 Jun 23. Blood. 2014. PMID: 24957147 Free PMC article.

8

Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia.

Irvine DA, Zhang B, Kinstrie R, Tarafdar A, Morrison H, Campbell VL, Moka HA, Ho Y, Nixon C, Manley PW, Wheadon H, Goodlad JR, Holyoake TL, Bhatia R, Copland M. Irvine DA, et al. Among authors: holyoake tl. Sci Rep. 2016 May 9;6:25476. doi: 10.1038/srep25476. Sci Rep. 2016. PMID: 27157927 Free PMC article.

9

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor-treated CML stem cells.

Zhang B, Chu S, Agarwal P, Campbell VL, Hopcroft L, Jørgensen HG, Lin A, Gaal K, Holyoake TL, Bhatia R. Zhang B, et al. Among authors: holyoake tl. Blood. 2016 Dec 8;128(23):2671-2682. doi: 10.1182/blood-2015-11-679928. Epub 2016 Sep 12. Blood. 2016. PMID: 27621307 Free PMC article.

10

Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.

Zhang B, Nguyen LXT, Li L, Zhao D, Kumar B, Wu H, Lin A, Pellicano F, Hopcroft L, Su YL, Copland M, Holyoake TL, Kuo CJ, Bhatia R, Snyder DS, Ali H, Stein AS, Brewer C, Wang H, McDonald T, Swiderski P, Troadec E, Chen CC, Dorrance A, Pullarkat V, Yuan YC, Perrotti D, Carlesso N, Forman SJ, Kortylewski M, Kuo YH, Marcucci G. Zhang B, et al. Among authors: holyoake tl. Nat Med. 2018 May;24(4):450-462. doi: 10.1038/nm.4499. Epub 2018 Mar 5. Nat Med. 2018. PMID: 29505034 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

215 results

Search Page

Filters