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Page 1
Novel hepatitis C virus replicon inhibitors: synthesis and structure-activity relationships of fused pyrimidine derivatives.
Krueger AC, Madigan DL, Beno DW, Betebenner DA, Carrick R, Green BE, He W, Liu D, Maring CJ, McDaniel KF, Mo H, Molla A, Motter CE, Pilot-Matias TJ, Tufano MD, Kempf DJ. Krueger AC, et al. Among authors: madigan dl. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2212-5. doi: 10.1016/j.bmcl.2012.01.096. Epub 2012 Feb 2. Bioorg Med Chem Lett. 2012. PMID: 22342631
Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors.
Maring CJ, Stoll VS, Zhao C, Sun M, Krueger AC, Stewart KD, Madigan DL, Kati WM, Xu Y, Carrick RJ, Montgomery DA, Kempf-Grote A, Marsh KC, Molla A, Steffy KR, Sham HL, Laver WG, Gu YG, Kempf DJ, Kohlbrenner WE. Maring CJ, et al. Among authors: madigan dl. J Med Chem. 2005 Jun 16;48(12):3980-90. doi: 10.1021/jm049276y. J Med Chem. 2005. PMID: 15943472
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides.
Krueger AC, Madigan DL, Jiang WW, Kati WM, Liu D, Liu Y, Maring CJ, Masse S, McDaniel KF, Middleton T, Mo H, Molla A, Montgomery D, Pratt JK, Rockway TW, Zhang R, Kempf DJ. Krueger AC, et al. Among authors: madigan dl. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3367-70. doi: 10.1016/j.bmcl.2006.04.015. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650764
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives.
Krueger AC, Madigan DL, Green BE, Hutchinson DK, Jiang WW, Kati WM, Liu Y, Maring CJ, Masse SV, McDaniel KF, Middleton TR, Mo H, Molla A, Montgomery DA, Ng TI, Kempf DJ. Krueger AC, et al. Among authors: madigan dl. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2289-92. doi: 10.1016/j.bmcl.2007.01.072. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17300933
A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
Sham HL, Zhao C, Stewart KD, Betebenner DA, Lin S, Park CH, Kong XP, Rosenbrook W Jr, Herrin T, Madigan D, Vasavanonda S, Lyons N, Molla A, Saldivar A, Marsh KC, McDonald E, Wideburg NE, Denissen JF, Robins T, Kempf DJ, Plattner JJ, Norbeck DW. Sham HL, et al. J Med Chem. 1996 Jan 19;39(2):392-7. doi: 10.1021/jm9507183. J Med Chem. 1996. PMID: 8558507
Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series.
Stoll V, Stewart KD, Maring CJ, Muchmore S, Giranda V, Gu YG, Wang G, Chen Y, Sun M, Zhao C, Kennedy AL, Madigan DL, Xu Y, Saldivar A, Kati W, Laver G, Sowin T, Sham HL, Greer J, Kempf D. Stoll V, et al. Among authors: madigan dl. Biochemistry. 2003 Jan 28;42(3):718-27. doi: 10.1021/bi0205449. Biochemistry. 2003. PMID: 12534284
Novel azacyclic ureas that are potent inhibitors of HIV-1 protease.
Sham HL, Zhao C, Marsh KC, Betebenner DA, Lin S, Rosenbrook W Jr, Herrin T, Li L, Madigan D, Vasavanonda S, Molla A, Saldivar A, McDonald E, Wideburg NE, Kempf D, Norbeck DW, Plattner JJ. Sham HL, et al. Biochem Biophys Res Commun. 1996 Aug 14;225(2):436-40. doi: 10.1006/bbrc.1996.1191. Biochem Biophys Res Commun. 1996. PMID: 8753780