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Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization.
Jin YR, Cho MR, Ryu CK, Chung JH, Yuk DY, Hong JT, Lee KS, Lee JJ, Lee MY, Lim Y, Yun YP. Jin YR, et al. Among authors: lim y. J Pharmacol Exp Ther. 2005 Jan;312(1):214-9. doi: 10.1124/jpet.104.073718. Epub 2004 Aug 24. J Pharmacol Exp Ther. 2005. PMID: 15328379
Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression.
Son DJ, Ha SJ, Song HS, Lim Y, Yun YP, Lee JW, Moon DC, Park YH, Park BS, Song MJ, Hong JT. Son DJ, et al. Among authors: lim y. J Pharmacol Exp Ther. 2006 May;317(2):627-34. doi: 10.1124/jpet.105.095901. Epub 2006 Jan 9. J Pharmacol Exp Ther. 2006. PMID: 16401728
Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular smooth muscle cell proliferation through suppressions of arachidonic acid liberation and ERK1/2 MAPK activation.
Son DJ, Lim Y, Park YH, Chang SK, Yun YP, Hong JT, Takeoka GR, Lee KG, Lee SE, Kim MR, Kim JH, Park BS. Son DJ, et al. Among authors: lim y. J Ethnopharmacol. 2006 Nov 3;108(1):148-51. doi: 10.1016/j.jep.2006.04.016. J Ethnopharmacol. 2006. PMID: 16766151
7,645 results