Grandl J - Search Results

1

Piezo proteins are pore-forming subunits of mechanically activated channels.

Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A. Coste B, et al. Among authors: grandl j. Nature. 2012 Feb 19;483(7388):176-81. doi: 10.1038/nature10812. Nature. 2012. PMID: 22343900 Free PMC article.

2

Pore region of TRPV3 ion channel is specifically required for heat activation.

Grandl J, Hu H, Bandell M, Bursulaya B, Schmidt M, Petrus M, Patapoutian A. Grandl J, et al. Nat Neurosci. 2008 Sep;11(9):1007-13. doi: 10.1038/nn.2169. Nat Neurosci. 2008. PMID: 19160498 Free PMC article.

3

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain.

Grandl J, Kim SE, Uzzell V, Bursulaya B, Petrus M, Bandell M, Patapoutian A. Grandl J, et al. Nat Neurosci. 2010 Jun;13(6):708-14. doi: 10.1038/nn.2552. Epub 2010 Apr 22. Nat Neurosci. 2010. PMID: 20414199 Free PMC article.

4

Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations.

Kim SE, Patapoutian A, Grandl J. Kim SE, et al. Among authors: grandl j. PLoS One. 2013;8(3):e59593. doi: 10.1371/journal.pone.0059593. Epub 2013 Mar 26. PLoS One. 2013. PMID: 23555720 Free PMC article.

5

Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization.

Dubin AE, Murthy S, Lewis AH, Brosse L, Cahalan SM, Grandl J, Coste B, Patapoutian A. Dubin AE, et al. Among authors: grandl j. Neuron. 2017 Apr 19;94(2):266-270.e3. doi: 10.1016/j.neuron.2017.03.039. Neuron. 2017. PMID: 28426961 Free PMC article.

6

Editorial Note to: Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization.

Dubin AE, Murthy S, Lewis AH, Brosse L, Cahalan SM, Grandl J, Coste B, Patapoutian A. Dubin AE, et al. Among authors: grandl j. Neuron. 2017 Apr 19;94(2):265. doi: 10.1016/j.neuron.2017.03.041. Neuron. 2017. PMID: 28426960 Free article. No abstract available.

7

Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.

Jabba S, Goyal R, Sosa-Pagán JO, Moldenhauer H, Wu J, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Jabba S, et al. Among authors: grandl j. Neuron. 2014 Jun 4;82(5):1017-31. doi: 10.1016/j.neuron.2014.04.016. Epub 2014 May 8. Neuron. 2014. PMID: 24814535 Free PMC article.

8

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.

Hu H, Grandl J, Bandell M, Petrus M, Patapoutian A. Hu H, et al. Among authors: grandl j. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1626-31. doi: 10.1073/pnas.0812209106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164517 Free PMC article.

9

Localized force application reveals mechanically sensitive domains of Piezo1.

Wu J, Goyal R, Grandl J. Wu J, et al. Among authors: grandl j. Nat Commun. 2016 Oct 3;7:12939. doi: 10.1038/ncomms12939. Nat Commun. 2016. PMID: 27694883 Free PMC article.

10

Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels.

Wu J, Lewis AH, Grandl J. Wu J, et al. Among authors: grandl j. Trends Biochem Sci. 2017 Jan;42(1):57-71. doi: 10.1016/j.tibs.2016.09.004. Epub 2016 Oct 12. Trends Biochem Sci. 2017. PMID: 27743844 Free PMC article. Review.

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