Xu W - Search Results

1

Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation.

Liu Q, Yao F, Chooi YH, Kang Q, Xu W, Li Y, Shao Y, Shi Y, Deng Z, Tang Y, You D. Liu Q, et al. Among authors: xu w. Chem Biol. 2012 Feb 24;19(2):243-53. doi: 10.1016/j.chembiol.2011.12.018. Chem Biol. 2012. PMID: 22365607 Free article.

2

Acyltransferase mediated polyketide release from a fungal megasynthase.

Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y. Xie X, et al. Among authors: xu w. J Am Chem Soc. 2009 Jun 24;131(24):8388-9. doi: 10.1021/ja903203g. J Am Chem Soc. 2009. PMID: 19530726 Free PMC article.

3

Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.

Li Y, Image II, Xu W, Image I, Tang Y, Image I. Li Y, et al. Among authors: xu w. J Biol Chem. 2010 Jul 23;285(30):22764-73. doi: 10.1074/jbc.M110.128504. Epub 2010 May 17. J Biol Chem. 2010. PMID: 20479000 Free PMC article.

4

Analysis of intact and dissected fungal polyketide synthase-nonribosomal peptide synthetase in vitro and in Saccharomyces cerevisiae.

Xu W, Cai X, Jung ME, Tang Y. Xu W, et al. J Am Chem Soc. 2010 Oct 6;132(39):13604-7. doi: 10.1021/ja107084d. J Am Chem Soc. 2010. PMID: 20828130 Free PMC article.

5

FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.

Meehan MJ, Xie X, Zhao X, Xu W, Tang Y, Dorrestein PC. Meehan MJ, et al. Among authors: xu w. Biochemistry. 2011 Jan 18;50(2):287-99. doi: 10.1021/bi1014776. Epub 2010 Dec 22. Biochemistry. 2011. PMID: 21069965 Free PMC article.

6

A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines.

Qiao K, Zhou H, Xu W, Zhang W, Garg N, Tang Y. Qiao K, et al. Among authors: xu w. Org Lett. 2011 Apr 1;13(7):1758-61. doi: 10.1021/ol200288w. Epub 2011 Mar 8. Org Lett. 2011. PMID: 21384820 Free PMC article.

7

Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation.

Zabala AO, Xu W, Chooi YH, Tang Y. Zabala AO, et al. Among authors: xu w. Chem Biol. 2012 Aug 24;19(8):1049-59. doi: 10.1016/j.chembiol.2012.07.004. Chem Biol. 2012. PMID: 22921072 Free PMC article.

8

Structural analysis of protein-protein interactions in type I polyketide synthases.

Xu W, Qiao K, Tang Y. Xu W, et al. Crit Rev Biochem Mol Biol. 2013 Mar-Apr;48(2):98-122. doi: 10.3109/10409238.2012.745476. Epub 2012 Dec 19. Crit Rev Biochem Mol Biol. 2013. PMID: 23249187 Free PMC article. Review.

9

The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene.

Lin HC, Chooi YH, Dhingra S, Xu W, Calvo AM, Tang Y. Lin HC, et al. Among authors: xu w. J Am Chem Soc. 2013 Mar 27;135(12):4616-9. doi: 10.1021/ja312503y. Epub 2013 Mar 19. J Am Chem Soc. 2013. PMID: 23488861 Free PMC article.

10

LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis.

Xu W, Chooi YH, Choi JW, Li S, Vederas JC, Da Silva NA, Tang Y. Xu W, et al. Angew Chem Int Ed Engl. 2013 Jun 17;52(25):6472-5. doi: 10.1002/anie.201302406. Epub 2013 May 7. Angew Chem Int Ed Engl. 2013. PMID: 23653178 Free PMC article.

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