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Adenovirus 5 E1A is responsible for increased expression of insulin receptor substrate 4 in established adenovirus 5-transformed cell lines and interacts with IRS components activating the PI3 kinase/Akt signalling pathway.
Shimwell NJ, Martin A, Bruton RK, Blackford AN, Sedgwick GG, Gallimore PH, Turnell AS, Grand RJ. Shimwell NJ, et al. Among authors: blackford an. Oncogene. 2009 Feb 5;28(5):686-97. doi: 10.1038/onc.2008.417. Epub 2008 Nov 24. Oncogene. 2009. PMID: 19029952
Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.
Townsend K, Mason H, Blackford AN, Miller ES, Chapman JR, Sedgwick GG, Barone G, Turnell AS, Stewart GS. Townsend K, et al. Among authors: blackford an. J Biol Chem. 2009 Dec 4;284(49):33939-48. doi: 10.1074/jbc.M109.009191. Epub 2009 Oct 13. J Biol Chem. 2009. PMID: 19826003 Free PMC article.
Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation.
Blackford AN, Patel RN, Forrester NA, Theil K, Groitl P, Stewart GS, Taylor AM, Morgan IM, Dobner T, Grand RJ, Turnell AS. Blackford AN, et al. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12251-6. doi: 10.1073/pnas.0914605107. Epub 2010 Jun 21. Proc Natl Acad Sci U S A. 2010. PMID: 20566845 Free PMC article.
35 results